Evidence map›Paper›PMID 40642631›Full record

ArticleSaudi journal of anaesthesia

Effectiveness of concentrated growth factor combined with bone powder in treating periodontal bone defects: A randomized controlled trial.

Liqin Wu, Haili Xu, Guodong Shen, Li Qin, Lijie Ma, Wenxia Shen

Abstract read
In one paragraph

Article in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liqin Wu *Department of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.
Haili Xu *Department of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.
Guodong ShenDepartment of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.
Li QinDepartment of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.
Lijie MaDepartment of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.
Wenxia ShenDepartment of Stomatology, Tongxiang Hospital of Traditional Chinese Medicine, Tongxiang City, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontal bone defects pose a significant challenge in stomatology, affecting dental stability and function. Objective: This study aimed to explore the clinical efficacy of concentrated growth factor (CGF) combined with artificial or autologous bone powder in the treatment of periodontal bone defects. Methods: A total of 106 patients with bone defects requiring surgical intervention were divided into two groups: the control group and the observation group. Preoperative data were analyzed, and postoperative periodontal indicators, bone resorption markers, and masticatory function were assessed at baseline and 2 weeks, 1 month, 3 months, and 6 months post surgery. Results: There were no significant differences in baseline characteristics between the two groups. The observation group showed improvements in periodontal probing depth, mucosal recession, plaque index, gingival index, gingival retreat index, and bone gla protein after 6 months. The masticatory function of the observation group was significantly better at 1 to 6 months post operation, and there were significant differences in postoperative pain levels at 6 months. Conclusion: CGF combined with artificial bone powder demonstrates superior performance in masticatory function recovery and periodontal clinical parameter restoration, indicating potential benefits for periodontal bone defect treatment.

Indexed as

Artificial bone powderautologous bone powderconcentrated growth factorperiodontal bone defectrandomized controlled trial

Identifiers

PMID40642631
PMCPMC12240508

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.