Evidence map›Paper›PMID 40642558›Full record

ArticleHealth science reports2025

The Association of Serum Level of TGF-β

Fatemeh Bakhshipour, Bita Bandar, Fatemeh Bineshfar, Najmeh Nameh Goshay Fard, Azar Babaahmadi, Najmaldin Saki, Kaveh Jaseb

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatemeh BakhshipourThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0003-0506-4874
Bita BandarThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0001-7280-6562
Fatemeh BineshfarThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.
Najmeh Nameh Goshay FardThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.
Azar BabaahmadiDepartment of Biostatistics and Epidemiology, School of Health Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.
Najmaldin SakiThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0001-8494-5594
Kaveh JasebThalassemia and Hemoglobinopathy Research Center, Health Research Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.ORCID https://orcid.org/0000-0002-3216-9113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Sickle cell anemia (SCA) is an inherited red blood cell disorder resulting from the polymerization of Hemoglobin S. Acute vaso-occlusive crisis and multiple organ damage are the most common complications of SCA. Because of its multifunctional role in inflammation, endothelial dysfunction, and fibrosis, TGF-β Methods: The level of TGF-β Results: The laboratory parameters including hemoglobin, red blood cell (RBC), hematocrit (HCT), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) were lower in SCA patients compared to the control group, and white blood count (WBC), red cell distribution width-coefficient of variation (RDW-CV), platelet count, mean platelet volume (MPV), and lactate dehydrogenase (LDH) were higher in these patients. No significant correlation was observed between laboratory parameters and Transforming Growth Factor Beta 1 (TGF-β Conclusion: We observed a higher prevalence of certain complications in SCA patients in the Arab population of Khuzestan Province. There was no significant correlation between the clinical manifestation of SCA and TGF-β

Indexed as

clinical manifestationhematological biomarkerssickle cell diseasetransforming growth factor beta 1 (TGF‐β1)

Identifiers

PMID40642558
PMCPMC12241425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.