Evidence map›Paper›PMID 40642508›Full record

ReviewFrontiers in endocrinology2025

Global research on endocrine disruptors as emerging hazards for human health and the environment.

Doris Klingelhöfer, Markus Braun, Janis Dröge, Dörthe Brüggmann, David A Groneberg

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Special Issue "Progress in Research on Endocrine-Disrupting Chemicals".International journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Doris KlingelhöferInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt, Germany.
Markus BraunInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt, Germany.
Janis DrögeInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt, Germany.
Dörthe BrüggmannInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt, Germany.
David A GronebergInstitute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt, Frankfurt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disruptors (EDs) contaminate nearly every ecosystem and are significantly associated with different neurological and neurodevelopmental disorders. To date, there is no comprehensive literature on global publication efforts. Since there are many unknown substances, modes of action, and risks of EDs, it is necessary to provide detailed insight into global publication patterns from temporal, regional, and socioeconomic perspectives. Hence, this review article provides background information for all stakeholders, from scientists to clinicians and policymakers. A disproportionate increase in research activity was observed, mainly from the USA and China, with a strong north-south divide. Multi-disciplinarity is characteristic, with a trend toward an ecological focus. Low- and middle-income economies are underrepresented in research on EDs. Therefore, global research needs to be refocused and expanded to more global approaches that take inspiration from the few successful collaborations with their synergistic effects.

Indexed as

Biomedical ResearchEndocrine DisruptorsEnvironmental ExposureEnvironmental PollutantsGlobal HealthHumansEndocrine DisruptorsEnvironmental Pollutantsbisphenol Aendocrine diseasesestrogenneurological diseasespharmaceuticalsthyroid hormones

Identifiers

PMID40642508
PMCPMC12240779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.