Evidence map›Paper›PMID 40642445›Full record

ArticleEJHaem2025

Physical Activity, Symptoms, Quality of Life and Exercise Program Preferences in People With Chronic Lymphocytic Leukaemia.

Ellie E Miles, Jennifer L Nicol, Hatti Fowler, Amelia Roberts, Andrew T Hulton, Caitlin Jeary, Renata Walewska, Sunil Iyengar, Erik D Hanson, CLL Support Association and 2 more

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ellie E MilesDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.
Jennifer L NicolSchool of Human Movement and Nutrition Sciences The University of Queensland Brisbane Australia.ORCID https://orcid.org/0000-0001-5049-8685
Hatti FowlerDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.
Amelia RobertsDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.
Andrew T HultonDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.
Caitlin JearyDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.
Renata WalewskaUniversity Hospitals Dorset Bournemouth UK.ORCID https://orcid.org/0009-0007-5693-2789
Sunil IyengarHaemato-Oncology Unit Royal Marsden Hospital London UK.
Erik D HansonDepartment of Exercise & Sport Science University of North Carolina Chapel Hill North Carolina USA.
CLL Support Association
Andrea SitlingerDepartment of Hematologic Malignancies and Cellular Therapies Duke University School of Medicine Durham North Carolina USA.
David B BartlettDepartment of Haematology, School of Biosciences University of Surrey Guildford UK.ORCID https://orcid.org/0000-0001-7838-898X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic lymphocytic leukaemia (CLL) has a heterogeneous lifelong course. While some patients never require treatment, most experience intermittent periods of active monitoring with other time points in active treatment. Most patients experience significant symptoms which negatively impact their quality of life (QoL). Although physical activity and exercise may help manage symptoms, it is unclear what disease-related factors drive the physical inactivity observed in people with CLL. Methods: This study explored physical activity among people with CLL and assessed differences and relationships in treatment stage, symptoms, quality of life, and preferences for physical activity using an online questionnaire. Results: A total of 128 individuals with CLL [66 M/62F: mean age 67 ± 9.1 years (range 38-91 years)] completed the questionnaire. Those who are being/have been treated ( Conclusion: These findings highlight a significant need for targeted interventions to increase physical activity, likely improving QoL, in people with CLL. Furthermore, there is considerable interest from the CLL community in receiving exercise guidance; however, factors such as treatment status and symptomology should be considered when developing CLL-specific exercise programs.

Indexed as

cancer symptomschronic lymphocytic leukaemiaphysical activityquality of lifesymptom management

Identifiers

PMID40642445
PMCPMC12244265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.