Evidence map›Paper›PMID 40642382›Full record

ArticleNature physics2022

Ciliary beating patterns map onto a low-dimensional behavioural space.

Veikko F Geyer, Jonathon Howard, Pablo Sartori

Erratum issuedAbstract read
In one paragraph

Article in Nature physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Quantification of flagellar gait changes with combined shape mode analysis and swimming simulations.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  4. Article
  5. Review
  6. Active fluctuations of axoneme oscillations scale with number of dynein motors.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Basal bodies bend in response to ciliary forces.Molecular biology of the cell · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Veikko F GeyerB CUBE-Center for Molecular Bioengineering, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0003-1884-2284
Jonathon HowardDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID 0000-0003-0086-1196
Pablo SartoriInstituto Gulbenkian de Ciência, Oeiras, Portugal.ORCID 0000-0002-3162-6730

Funding

Microtubule Severing and Regrowth by SpastinR01GM139337 · NIGMS · YALE UNIVERSITY · PI HOWARD, JONATHON · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM139337
6 · The paper itself

Abstract

Biological systems are robust to perturbations at both the genetic and environmental levels, although these same perturbations can elicit variation in behaviour. The interplay between functional robustness and behavioural variability is exemplified at the organellar level by the beating of cilia and flagella. Cilia are motile despite wide genetic diversity between and within species, differences in intracellular concentrations of ATP and calcium, and considerable environment fluctuations in temperature and viscosity. At the same time, these perturbations result in a variety of spatio-temporal patterns that span a rich behavioural space. To investigate this behavioural space we analysed the dynamics of isolated cilia from the unicellular algae

Identifiers

PMID40642382
PMCPMC12242449

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.