ArticleFrontiers in neurology2025
Alterations in frontotemporal cerebral activity specific to auditory verbal hallucination during verbal fluency task in schizophrenia: a fNIRS study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Patients with auditory verbal hallucination (AVH) may experience significant occupational and social functional disabilities, which bring a heavy burden to their families and society. Although neuroimaging studies have explored the brain regions associated with AVH and proposed models to explain AVH, the potential pathological mechanisms are not clear. Functional near-infrared spectroscopy (fNIRS) is a portable and suitable measurement, particularly in exploring brain activation during related tasks. Hence, our researchers aimed to explore the differences in the cerebral hemodynamic function between patients with schizophrenia with AVH (SZ-AVHs) and patients with schizophrenia without AVH (SZ-nAVHs) through fNIRS to examine neural abnormalities associated more specifically with AVH. Methods: A 52-channel functional near-infrared spectroscopy system was used to monitor hemodynamic changes in SZ-AVHs ( Results: Our results showed that the integral values of the SZ-AVHs were significantly higher than those of the SZ-nAVHs in the left STC [ Discussion: Our findings indicate that SZ-AVHs exhibited lower activation in the left STC and Slower response speed in the right vlPFC than SZ-nAVHs.
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