Evidence map›Paper›PMID 40642179›Full record

ArticleWomen's health reports (New Rochelle, N.Y.)2025

Maria Teresa Schettino, Maria Giovanna Vastarella, Gaetano Riemma, Ernesta Dores, Fabio Turco, Pasquale De Franciscis

Abstract read
In one paragraph

Article in Women's health reports (New Rochelle, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Teresa SchettinoDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Maria Giovanna VastarellaDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Gaetano RiemmaDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.
Ernesta DoresDepartment of Acceptance, Emergency Room and Emergency Medicine, San Carlo Hospital, Potenza, Italy.
Fabio TurcoCannabiscientia SA, Lugano, Switzerland.ORCID https://orcid.org/0009-0003-3489-0179
Pasquale De FranciscisDepartment of Women, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Dysmenorrhea causes intense menstrual pain and symptoms such as cramps, headaches, and nausea. Nonsteroidal anti-inflammatory drugs (NSAIDs) offer relief but have limited efficacy and side effects, prompting interest in alternative therapies. This study evaluated a food supplement with Methods: This single-center retrospective study included 33 women aged 20-35 with dysmenorrhea-related symptoms who had experienced insufficient relief from NSAIDs alone. Participants received the food supplement in addition to NSAIDs over three menstrual cycles. The primary outcome was the reduction in pain intensity. Secondary outcomes included changes in NSAIDs use and symptom prevalence ( Results: After 3 months, general pain and migraine decreased significantly, with mean Numeric Rating Scale scores decreasing from 8.2 (±1.02) to 6.8 (±1.08; Conclusions: These preliminary findings suggest that this food supplement may effectively reduce dysmenorrhea symptoms and reliance on NSAIDs in patients with insufficient response to conventional therapies. Further validation through randomized controlled trials is needed to confirm these results and establish the supplement's role in dysmenorrhea management.

Indexed as

anti-inflammatorycomplementary therapyherbal extractNSAIDs reductionpain managementsymptom relief

Identifiers

PMID40642179
PMCPMC12241841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.