Evidence map›Paper›PMID 40642158›Full record

ArticlePCN reports : psychiatry and clinical neurosciences2025

Association between pharmacological guideline adherence and actigraphy-measured sleep variables in long-term hospitalized patients with schizophrenia.

Kentaro Saito, Yusuke Arai, Daimei Sasayama, Toshinori Nakamura, Kazuhiro Suzuki, Mika Koido, Reiko Sahara, Yuka Nakajima, Aya Horiuchi, Fumiya Fukui and 2 more

Abstract read
In one paragraph

Article in PCN reports : psychiatry and clinical neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kentaro SaitoDepartment of Psychiatry Kurita Hospital Nagano Japan.ORCID https://orcid.org/0009-0001-6535-4585
Yusuke AraiDepartment of Psychiatry Kurita Hospital Nagano Japan.ORCID https://orcid.org/0000-0002-3155-6971
Daimei SasayamaDepartment of Psychiatry Shinshu University School of Medicine Matsumoto Japan.ORCID https://orcid.org/0000-0003-3450-7283
Toshinori NakamuraDepartment of Psychiatry Shinshu University School of Medicine Matsumoto Japan.
Kazuhiro SuzukiDepartment of Psychiatry Shinshu University School of Medicine Matsumoto Japan.
Mika KoidoDepartment of Psychiatry Kurita Hospital Nagano Japan.
Reiko SaharaDepartment of Psychiatry Kurita Hospital Nagano Japan.
Yuka NakajimaDepartment of Psychiatry Kurita Hospital Nagano Japan.
Aya HoriuchiDepartment of Psychiatry Kurita Hospital Nagano Japan.
Fumiya FukuiDepartment of Psychiatry Kurita Hospital Nagano Japan.
Kazuaki KuraishiDepartment of Psychiatry Kurita Hospital Nagano Japan.
Shinsuke WashizukaDepartment of Psychiatry Shinshu University School of Medicine Matsumoto Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Improving sleep quality is a crucial clinical objective in schizophrenia care; however, the association between evidence-based pharmacological treatment and sleep outcomes remains unclear. This study aimed to examine whether guideline adherence, assessed using the individual fitness score (IFS), correlated with actigraphy-measured sleep in long-term hospitalized patients. Methods: We included 40 inpatients aged <65 years who were diagnosed with schizophrenia. Guideline adherence was assessed using the IFS and actigraphy was used to measure total sleep time (TST), sleep latency (SL), and sleep efficiency (SE). In 33 patients, these measures were re-evaluated after 6 months. Results: Cross-sectional analysis showed a positive correlation between IFS and TST (rho = 0.362, Conclusion: In this cohort of long-term hospitalized patients with schizophrenia, guideline adherence (higher IFS) was associated with increased TST. However, no clear longitudinal effects of IFS on sleep were observed. These findings emphasize the importance of guideline adherence in optimizing sleep, although extended follow-ups and larger sample sizes are required to confirm the long-term impact of guideline-based treatments on sleep in patients with schizophrenia.

Indexed as

guidelinehypnoticpharmacotherapyschizophreniasleep

Identifiers

PMID40642158
PMCPMC12241822

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.