Evidence map›Paper›PMID 40642131›Full record

ArticleJournal of general and family medicine2025

Drug-induced liver injury associated with exposure to Hangeshashinto.

Kimitoshi Kubo, Issei Ashida, Noriko Kimura

Abstract read
In one paragraph

Article in Journal of general and family medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Drug-induced liver injury associated with exposure to Hangeshashinto.Journal of general and family medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kimitoshi KuboDepartment of Gastroenterology National Hospital Organization Hakodate Medical Center Hakodate Hokkaido Japan.ORCID https://orcid.org/0000-0002-1424-1011
Issei AshidaDepartment of Gastroenterology National Hospital Organization Hakodate Medical Center Hakodate Hokkaido Japan.
Noriko KimuraDepartment of Pathology National Hospital Organization Hakodate Medical Center Hakodate Hokkaido Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While Kampo medicines are deemed relatively safe and associated with few adverse effects, primary care physicians are well advised to be aware of the risk of drug-induced liver injury in patients prescribed Kampo medicines containing Scutellariae radix, such as Hangeshashinto, in clinical practice and to closely monitor their clinical course.

Indexed as

baicalindrug‐induced liver injuryHangeshashintoKampo medicinesScutellariae radix

Identifiers

PMID40642131
PMCPMC12237816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.