Evidence map›Paper›PMID 40642013›Full record

ArticleFrontiers in pharmacology2025

Hydrogen sulfide alleviates high-salt-stimulated myocardial fibrosis through inhibiting hypoxia-inducible factor-1α.

Qian Peng, Pan Huang, Boyang Lv, Chaoshu Tang, Hongfang Jin, Yaqian Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qian Peng *Department of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, China.
Pan Huang *Department of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, China.
Boyang LvDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, China.
Chaoshu TangDepartment of Physiology and Pathophysiology, Peking University Health Science Center, Beijing, China.
Hongfang JinDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, China.
Yaqian HuangDepartment of Pediatrics, Children's Medical Center, Peking University First Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endogenous hydrogen sulfide (H Objective: The contribution of the H Methods: We used primary rat cardiac fibroblasts stimulated with high-salt medium and an MF model induced by a high-salt diet in Dahl salt-sensitive rats. Sodium hydrosulfide (NaHS), a commonly used H Results: High-salt exposure reduced H Conclusion: In conclusion, H

Indexed as

cardiac fibroblastsHIF-1αhigh-salt diethydrogen sulfidemyocardial fibrosis

Identifiers

PMID40642013
PMCPMC12240975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.