Evidence map›Paper›PMID 40641729›Full record

SynthesisSultan Qaboos University medical journal2025

Efficacy of Hormonal and Non-Hormonal Vaginal Gel Preparations on the Female Sexual Satisfaction Index in Postmenopausal Women with Sexual Dysfunction Syndrome:

Ahmed Soliman, Hanaa Alrashidi, Mohamed A Mohamed, Reem Ghorab, Nihal Al Riyami, Ahmed S A Ashour, Yasmine A Mohammed, Ahmed H Saad

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmed SolimanFaculty of Medicine, Research Department, Mansoura University, Mansoura, Egypt.
Hanaa AlrashidiKuwait Institute for Medical Specializations, Kuwait City, Kuwait.
Mohamed A MohamedFaculty of Medicine, Zagazig University, Zagazig, Egypt.
Reem GhorabFaculty of Medicine, Misr University for Science and Technology, 6th of October City, Egypt.
Nihal Al RiyamiDepartment of Obstetrics & Gynecology, Sultan Qaboos University, Muscat, Oman.
Ahmed S A AshourDepartment of Obstetrics & Gynecology, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Yasmine A MohammedFaculty of Medicine, Assiut University, Assiut, Egypt.
Ahmed H SaadDepartment of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis aimed to compare the efficacy of vaginal gel preparations versus placebo in postmenopausal women with sexual dysfunction syndrome. Searches of electronic databases from inception to January 2023 identified 8 trials (N = 672) that reported the Female Sexual Function Index (FSFI) and compared hormonal (oestrogen, oxytocin) and/or non-hormonal (chamomile, fennel) interventions against placebo. The Cochrane Risk of Bias tool was used to assess studies' quality. The vaginal gel group had a significantly higher total FSFI endpoint score (mean difference [MD] = 6.67, 95% confidence interval [CI]: 3.79-9.55;

Indexed as

PostmenopauseSexual Dysfunction, PhysiologicalVaginal Creams, Foams, and JelliesAdministration, IntravaginalFemaleHumansMiddle AgedVaginal Creams, Foams, and JelliesChamomileEstrogenMenopauseMeta-AnalysisPsychological Sexual Dysfunction

Identifiers

PMID40641729
PMCPMC12244233

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.