Evidence map›Paper›PMID 40641669›Full record

GuidelineTransplant international : official journal of the European Society for Organ Transplantation2025

Optimizing the Use of Deceased Donor Kidneys at Risk of Discard: A Clinical Practice Guideline.

Joanna C Dionne, Patricia Campbell, Héloïse Cardinal, Tatiana Giannidis, Aviva Goldberg, S Joseph Kim, Greg Knoll, Michel Pâquet, Christina Parsons, Yuhong Yuan and 1 more

Abstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joanna C DionneDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Patricia CampbellDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Héloïse CardinalCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Tatiana GiannidisDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Aviva GoldbergDepartment of Pediatrics and Child Health, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada.
S Joseph KimDivision of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Greg KnollDivision of Nephrology, Department of Medicine, University of Ottawa and the Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Michel PâquetDivision of Nephrology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Christina ParsonsCanadian Blood Services, Ottawa, ON, Canada.
Yuhong YuanDivision of Gastroenterology, McMaster University, Hamilton, ON, Canada.
Rahul MainraDivision of Nephrology, Department of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Underutilization of deceased donor organs has worsened the gap in the number of kidneys available for transplantation. The purpose of this clinical practice guideline is to provide recommendations on the utilization of donor kidneys at risk of discard. Six conditional recommendations were made all with very low certainty of evidence: 1) We suggest utilizing extended criteria donor (ECD) kidneys for transplantation rather than remaining on the wait list and continuing with dialysis; 2) We suggest utilizing kidneys from ECD versus non-ECD in selected transplant candidates; 3) We suggest that organs from older kidney donors can be used in selected transplant candidates who may derive benefit from them; 4) We suggest that kidneys from deceased donors with acute kidney injury can be used for transplantation based on clinician assessment and donor factors; 5) We suggest that donor kidneys with acute kidney injury from either ECD or non-ECD be used for kidney transplantation; 6) We suggest using kidneys from donors after death determination by circulatory criteria for transplantation. This clinical practice guideline provides evidence for the use of deceased donor kidneys that are at risk of discard and may improve the shared decision-making between transplant physicians and wait-listed patients.

Indexed as

Donor SelectionKidney TransplantationTissue and Organ ProcurementTissue DonorsAcute Kidney InjuryCadaverHumansWaiting Listsclinical practice guidelinedecision makingkidney transplantorgan discardutilization

Identifiers

PMID40641669
PMCPMC12240869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.