ArticleOman medical journal2025
Antimicrobial Management of Urinary Tract Infections: Insights from a Tertiary Care Hospital in Oman.
Article in Oman medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: To assess treatment initiatives in symptomatic and asymptomatic urinary tract infection (UTI) cases, identify effective antibiotics based on culture reports, and evaluate secondary factors such as symptoms, urine white blood cells, culture correlation, prevalent microbial flora, empirical antibiotic efficacy, and prevalence of multidrug resistance (MDR). Methods: A retrospective analysis of urological cases with microbial growth on culture was conducted. Data on demographics, symptoms, urinalysis, culture analysis, antibiotic sensitivity, and MDR status were collected and statistically analyzed. Results: Out of 223 cases included in the study, 191 were symptomatic and 32 were asymptomatic. Conclusions: Nitrofurantoin was highly effective for UTIs; however, multidrug-resistant strains remain a concern. With limited access to minimum inhibitory concentration results and culture sensitivity tests during the initial patient visit, physicians prescribing first-line treatments for suspected cases of resistance must carefully evaluate clinical presentation, patient history, and local resistance patterns. Subsequent treatments should be based on culture sensitivity results and clinical guidelines. This study is particularly relevant in the Gulf Cooperation Council region due to its distinct epidemiological and clinical landscape.
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