Evidence map›Paper›PMID 40641607›Full record

ArticleSexual medicine2025

Analysis of surgical complications and risk factors in genital feminization surgery: a retrospective cohort study of 407 transgender women.

Fériel Ferchichi, Nicolas Morel-Journel, Damien Carnicelli, Lucas Freton, Lucie Jurek, Alain Ruffion, François-Xavier Madec, Paul Neuville

Abstract read
In one paragraph

Article in Sexual medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fériel FerchichiUrology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.
Nicolas Morel-JournelUrology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.
Damien CarnicelliUrology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.
Lucas FretonUrology Department, Centre Hospitalier Universitaire de Rennes, Rennes 35000, France.
Lucie JurekChild and Adolescent Unit, Psychiatry Department, Centre Hospitalier Le Vinatier, 69678 Lyon, France.
Alain RuffionUrology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.
François-Xavier MadecUrology Department, Hopital Foch, Suresnes  92150, France.
Paul NeuvilleUrology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Penile inversion vulvo-vaginoplasty with addition of a scrotal skin graft is a widely used technique in genital feminizing surgery for trans women. Aim: To identify the types and frequencies of complications following genital feminizing surgery and assess associated risk factors. Methods: A retrospective review was conducted on all trans women who underwent primary genital feminizing surgery at Lyon Sud University Hospital between 2008 and 2022. Inclusion criteria were age over 18 and a minimum follow-up of 1 year. Data were collected from electronic medical records and included demographic and clinical characteristics, surgical details, intraoperative events, postoperative complications, and revision procedures. Outcomes: The study focused on the incidence of intraoperative, early, and late postoperative complications, as well as the frequency and types of surgical revisions. Results: Among 407 patients (mean (SD) age of 38.6 (12.7) years, mean (SD) BMI of 24.7), intra-operative rectal injury occurred in 5 patients (1.2%). Early graft failure requiring revision was seen in 1%, and 23.1% underwent secondary revisions. Late complications included recto-neovaginal fistula (0.5%) and vaginal stenosis requiring revision (3.4%). Labiaplasty was the most frequent revision procedure ( Clinical Implications: Clear, individualized preoperative counseling is essential to prepare patients for the potential need for revision surgery. Strengths & Limitations: This study benefits from a large sample size and long follow-up but is limited by its retrospective design and reliance on electronic records. Conclusion: Penile inversion vulvo-vaginoplasty with scrotal skin graft is a generally safe procedure; detailed knowledge of complications supports better patient counseling and informed decision-making.

Indexed as

genital feminizing surgerygenital reassignmentgenital reconstructiontranswomanvulvo-vaginoplasty

Identifiers

PMID40641607
PMCPMC12240733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.