Evidence map›Paper›PMID 40641596›Full record

ArticleBrain communications2025

Feasibility trial of a self-help digital intervention for functional cognitive disorder.

Verónica Cabreira, Lisbeth Frostholm, Jon Stone, Alan Carson

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Unmet needs in functional neurological disorder related to digital healthcare.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Verónica CabreiraCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.ORCID https://orcid.org/0000-0001-9945-7681
Lisbeth FrostholmDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 118200 Aarhus N, Denmark.
Jon StoneCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.ORCID https://orcid.org/0000-0001-9829-8092
Alan CarsonCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.ORCID https://orcid.org/0000-0002-7425-0964

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional cognitive disorder is the cognitive subtype of functional neurological disorders. Symptoms are associated with a high level of distress and typically arise due to various risk factors including abnormal focused attention, high memory expectations and poor metacognition. Easily accessible specialized treatments for functional cognitive disorder are needed. Digital interventions are less costly and scalable and allow individuals to engage in self-care in a flexible manner. In this study, we aimed to (i) evaluate the feasibility and safety of a novel self-help digital intervention based on principles of cognitive behavioural therapy and related approaches, (ii) explore preliminary effects of this intervention and (iii) learn about participants' experience with the intervention. Patients were recruited via a neuropsychiatry clinic. They autonomously completed a 6-week intervention, with phone and email technical support, and were assessed at baseline and at the end of the intervention, using self-reported questionnaires. Besides feasibility outcomes, main measures were the metamemory in adulthood questionnaire, subjective memory complaints, clinical global impression of change, Brief Illness Perception Questionnaire, Behavioural Responses to Illness Questionnaire, Compensatory Cognitive Strategies Questionnaire, depressive and anxiety symptoms, work and social functioning and quality of life. A within-group design was employed. Means, standard deviations and effect sizes were estimated. Post-treatment semi-structured interviews were conducted to further explore the acceptability and usability of the programme. Of the 38 patients eligible, 37 completed the baseline questionnaires (97% recruitment rate). Thirty started the intervention (54% female, mean age 50.4). Four dropped out (4/30, 13%), with 23/30 (77%) completing three or more modules, and the attrition rate was 37%. Twenty-seven treatment-related negative effects were reported (5% of total). Overall satisfaction with the programme was high with 62% (16/26) reporting feeling 'satisfied' or 'very satisfied'. Sixteen (62%) reported improvement in their cognitive symptoms ('minimally improved', 'much improved' and 'very much improved'). Paired

Indexed as

cognitive behavioural therapyfeasibilityfunctional cognitive disorderinternet interventionmobile app

Identifiers

PMID40641596
PMCPMC12241858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.