Evidence map›Paper›PMID 40641317›Full record

ArticleAngewandte Chemie (International ed. in English)2025

On-Demand Photodegradable and Thermo-Reversible, Soft, Transparent Dithioacetal Hydrogels.

Maria Psarrou, Ioanna Chatzaki, Antonis Mavromanolakis, Theodore Manouras, Dimitris Vlassopoulos, Maria Vamvakaki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria PsarrouDepartment of Materials Science and Engineering, University of Crete, Heraklion, Crete, 700 13, Greece.
Ioanna ChatzakiDepartment of Materials Science and Engineering, University of Crete, Heraklion, Crete, 700 13, Greece.
Antonis MavromanolakisInstitute of Electronic Structure and Laser, Foundation for Research and Technology-Hellas, Heraklion, Crete, 700 13, Greece.
Theodore ManourasDepartment of Materials Science and Engineering, University of Crete, Heraklion, Crete, 700 13, Greece.
Dimitris VlassopoulosDepartment of Materials Science and Engineering, University of Crete, Heraklion, Crete, 700 13, Greece.
Maria VamvakakiDepartment of Materials Science and Engineering, University of Crete, Heraklion, Crete, 700 13, Greece.ORCID https://orcid.org/0000-0003-2150-9415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimuli-reversible, chemically cross-linked polymers capable of altering their physicochemical and mechanical properties on demand, upon application of external stimuli (e.g., light, temperature), are highly desirable for the development of multifunctional materials. Herein, we report a facile chemical platform for the synthesis of photodegradable and thermo-reversible, model hydrogels consisting of poly(ethylene glycol) (PEG) as the elastic strands and dithioacetal moieties at the cross-link points. The gels were synthesized via an acid-catalyzed step-growth reaction of a difunctional PEG-thiol macromer with a wisely selected aromatic dialdehyde cross-linker. The formation of the photosensitive dithioacetal bonds at the cross-links rendered the hydrogels photodegradable, whereas the production of the initial comonomers as the main photoproducts after irradiation endowed the material with thermoreversible properties. The linear viscoelastic behavior of water-swollen gels, their photodegradation under UV (λ = 254 nm) irradiation at very low intensity (0.063 mW cm

Indexed as

Photodegradable hydrogelsRecyclable networksStimuli‐reversible networks

Identifiers

PMID40641317
PMCPMC12402857

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.