Evidence map›Paper›PMID 40640902›Full record

ArticleBMC psychology2025

The mediating role of resilience in the relationships between posttraumatic growth and depression as well as anxiety among survivors of nasopharyngeal carcinoma: a cross-sectional study.

Shenghao Wang, Liying Lai, Yang Deng, Yuan Zhang, Yuqi Cai, Wenyan Huang, Yuantao Hao, Fengsu Hou, Jinghua Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shenghao WangDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Liying LaiDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Yang DengDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Yuan ZhangSun Yat-sen Global Health Institute, Sun Yat-sen University, Guangzhou, 510080, China.
Yuqi CaiDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
Wenyan HuangZhuhai Center for Disease Control and Prevention, Zhuhai, 519000, China.
Yuantao HaoPeking University Center for Public Health and Epidemic Preparedness & Response, Peking University, 38 Xueyuan Road, Bei-jing, 100191, China.
Fengsu HouSchool of Public Health, Shenzhen University Medical School, Shenzhen University, Shenzhen, 518000, China. fengsu_hou@szu.edu.cn.
Jinghua LiSun Yat-sen Global Health Institute, Sun Yat-sen University, Guangzhou, 510080, China. lijinghua@um.edu.mo.

Funding

Fundamental Research Funds for the Central Universities, Sun Yat-sen University 24ykqb007Sun Yat-Sen University Young Teacher Incubation Foundation Ref#20ykpy84
6 · The paper itself

Abstract

backgroundNasopharyngeal carcinoma (NPC) survivors demonstrate heightened vulnerability to depression and anxiety, while posttraumatic growth (PTG) and resilience have been reported as important protective factors for mental health. This study examined the mediating role of resilience in the associations between PTG and both depression and anxiety among NPC survivors.

methodsA total of 773 NPC survivors were recruited through convenience sampling at Sun Yat-sen University Cancer Center (Guangzhou, China). Participants completed a self-administered structured questionnaire measuring sociodemographic and clinical characteristics, depression (PHQ-9), anxiety (GAD-7), posttraumatic growth (PTGI), and resilience (CD-RISC10). Mediation analyses were performed using structural equation modeling.

resultsThe average time since cancer diagnosis was 2.68 (SD = 1.80) years, with 55.0% diagnosed for over 2 years. Among the participants, 44.2% reported mild to severe depressive symptoms, and 35.3% reported mild to severe anxiety. Higher PTG was significantly associated with lower symptoms of depression (β = -0.23, p < 0.001) and anxiety (β = -0.19, p < 0.001). Additionally, greater resilience was associated with reduced symptoms of depression (β = -0.37, p < 0.001) and anxiety (β = -0.33, p < 0.001). Further, resilience fully mediated the relationship between PTG and both anxiety (86.50%) and depression (74.13%).

conclusionPTG and resilience are negatively associated with depression and anxiety in NPC survivors, with resilience acting as a complete mediator in these relationships.

Indexed as

AnxietyCancer SurvivorsDepressionNasopharyngeal CarcinomaNasopharyngeal NeoplasmsPosttraumatic Growth, PsychologicalResilience, PsychologicalAdultAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesAnxietyDepressionNasopharyngeal carcinomaPosttraumatic growthResilience

Identifiers

PMID40640902
PMCPMC12247339

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.