Evidence map›Paper›PMID 40640744›Full record

ArticleBMC geriatrics2025

Emergence of co-infection with Cryptococcus neoformans and Acinetobacter baumannii in older people with systemic lupus erythematosus.

Chongmei Tian, Yuejuan Fang, Zhixin You, Huijiao Li, Yaping Zhao, Jingbai Chen, Su Dong, Lihua Jiang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chongmei Tian *Department of Pharmacy, Shaoxing Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China.
Yuejuan Fang *Department of Pharmacy, Quzhou Maternal and Child Health Care Hospital, Quzhou, 324000, China.
Zhixin You *Department of Respiratory Medicine, Shaoxing Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China.
Huijiao LiDepartment of Respiratory Medicine, Shaoxing Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China.
Yaping ZhaoDepartment of Pharmacy, Shaoxing Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China.
Jingbai ChenDepartment of Pharmacy, Shaoxing Hospital of Traditional Chinese Medicine, Affiliated to Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China.
Su DongDepartment of Clinical Laboratory, Shaoxing Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, China. 31671963@qq.com.
Lihua JiangDepartment of Laboratory Medicine, Tongxiang First People's Hospital, Tongxiang, 314500, China. 18857377729@163.com.

Funding

Chinese medicine science foundation of Zhejiang Province, China 2023ZL729Chinese medicine science foundation of Zhejiang Province, China 2024ZR180Medical and Health Technology Projects of Zhejiang Province, China 2023KY1270Shaoxing Health Science and Technology Project, China 2023SKY058Shaoxing Science and Technology Program 2024A14018Special project of Zhejiang Pharmaceutical Society 2024ZYYJ08State Key Laboratory of Neurology and Oncology Drug Development Program SKLSIM-F-2024
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a common autoimmune disease affecting various organs. Cryptococcus neoformans, an environmental yeast that is heavily dependent on the complement cascade for natural host defense, is produced via inhalation in immunocompromised patients. The fungal pathogen, C. neoformans, can cause life-threatening infections in patients with SLE. Acinetobacter baumannii is a nosocomial pathogen that causes healthcare-associated infections, particularly in immunocompromised and critically ill patients. However, reports of co-infection with C. neoformans and A. baumannii in patients with SLE are scarce. We report an interesting case of co-infection with C. neoformans and A. baumannii in an 85-year-old man presented with cough, expectoration, chest tightness, and shortness of breath five months after diagnosis of SLE. The patient recovered gradually after 18 days of antimicrobial therapy. Coinfection with C. neoformans and A. baumannii in patients with SLE is rare, difficult to diagnose early, and has a high mortality rate. Accurate diagnosis and timely treatment are lifesaving.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsCoinfectionCryptococcosisCryptococcus neoformansLupus Erythematosus, SystemicAged, 80 and overHumansMaleAcinetobacter baumanniiCo-infectionCryptococcus neoformansPneumonitisSystemic lupus erythematosus

Identifiers

PMID40640744
PMCPMC12243340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.