Evidence map›Paper›PMID 40640721›Full record

Trial reportBMC anesthesiology2025

Anterior quadratus lumborum block is superior to erector spinae plane block for analgesia after renal transplantation: a randomized controlled trial.

Yi An, Lixia Li, Zhongjia Li, Fei Lan, Tianlong Wang, Tongwen Ou, Chuanyu Liang, Pei Wang, Xuefei Jia, Hongyi Song and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07346417 (Erector Spinae Plane Block Versus Quadratus Lumborum Block for Post Operative Analgesia in Pediatric Kidney Surgery), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07346417 nanot yet recruitingnot on this map

Erector Spinae Plane Block Versus Quadratus Lumborum Block for Post Operative Analgesia in Pediatric Kidney Surgery

TypeinterventionalSponsorAssiut UniversityRan2025 to 2028Enrolled100ConditionsKidney DiseasesArmsQuadratus lumborum block teqnique, Erector spinae plane block Technique
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Abdominal Organ Transplantation: Noteworthy Literature in 2025.Seminars in cardiothoracic and vascular anesthesia · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yi AnDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Lixia LiDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Zhongjia LiDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Fei LanDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Tianlong WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Tongwen OuDepartment of Urology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Chuanyu LiangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Pei WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Xuefei JiaDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Hongyi SongDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Ke CuiDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Huifang LuoDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Lei ZhaoDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China. zhaoalei@sina.com.

Funding

National Natural Science Foundation of China 62376168Xuanwu Hospital Science Program for Fostering Young Scholars QNPY2020027
6 · The paper itself

Abstract

backgroundClinical evidence revealed patients suffered from moderate to severe pain after renal transplantation. Both quadratus lumborum block (QLB) and erector spinae plane block (ESPB) are effective strategies in perioperative analgesia. This trial aims to detect whether truncal blocks are utility in alleviating postoperative pain after renal transplantation.

methodsNinety-two patients underwent renal transplantation were recruited and randomized to QLB group, ESPB group and control group (C group). Patients in QLB or ESPB group received 0.5% ropivacaine 30 mL for single injection before surgery respectively and patients in C group did not receive any local anesthetic injection before general anesthesia induction. Postoperative pain intensity was evaluated at 0, 2, 4, 6, 8, 12, 24 and 48 h after surgery in the present study. Intraoperative medication and postoperative complications were also recorded and analyzed.

resultsThe proportion of moderate to severe pain in the first 24 h when moving was lowest in the QLB group (41.9% in QLB group vs. 83.9% in ESPB group vs. 96.7% in C group, P < 0.001). Pain intensity score (NRS) in the QLB group was significantly improved at 0, 2, 4, 6, 8 and 12 h after surgery (P < 0.05). Area under curve (AUCs) of NRS scores were significantly lower in the QLB group than in the ESPB group and C group (P < 0.001). We also observed a reduction of remifentanil consumption in the QLB group than in either the ESPB or C groups (P = 0.008 and P < 0.001, respectively).

conclusionsQuadratus lumborum block before surgery more effectively suppressed pain after renal transplantation relative to erector spinae plane block.

trial registrationThis study was registered on October 2, 2020. ChiCTR2000038803.

Indexed as

AnalgesiaKidney TransplantationNerve BlockPostoperative PainAbdominal MusclesAdultAnesthetics, LocalFemaleHumansMaleMiddle AgedPain MeasurementParaspinal MusclesRopivacaineAnesthetics, LocalRopivacaineAcute painErector spinae plane blockQuadratus lumborum blockRenal transplantationUltrasound-guided

Identifiers

PMID40640721
PMCPMC12243212

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.