Evidence map›Paper›PMID 40640639›Full record

ArticleMusculoskeletal surgery2026

Internal fixation through posterolateral approach versus Ilizarov external fixation for treatment of aseptic distal tibia nonunion: a comparative analysis.

S Cerbasi, G Di Sante, N Rani, N Del Piccolo, C Stagni, A Maresca, P Vitale, D Dallari, R Pascarella

Abstract readComparative Study
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In one paragraph

Article in Musculoskeletal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

S CerbasiUnit of Orthopaedics and Trauma Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy. simone.cerbasi@libero.it.
G Di SanteUnit of Orthopaedics and Trauma Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.
N RaniReconstructive Orthopedic Surgery and Innovative Techniques Musculoskeletal Tissue Bank, Rizzoli IRCCS Orthopedic Institute, Bologna, Italy.
N Del PiccoloReconstructive Orthopedic Surgery and Innovative Techniques Musculoskeletal Tissue Bank, Rizzoli IRCCS Orthopedic Institute, Bologna, Italy.
C StagniReconstructive Orthopedic Surgery and Innovative Techniques Musculoskeletal Tissue Bank, Rizzoli IRCCS Orthopedic Institute, Bologna, Italy.
A MarescaUnit of Orthopaedics and Trauma Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.
P VitaleUnit of Orthopaedics and Trauma Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.
D DallariReconstructive Orthopedic Surgery and Innovative Techniques Musculoskeletal Tissue Bank, Rizzoli IRCCS Orthopedic Institute, Bologna, Italy.
R PascarellaUnit of Orthopaedics and Trauma Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDistal tibia nonunion poses a serious therapeutic challenge for orthopedic surgeons. Bone loss and soft tissue damage is relatively common. The aim of this study was to compare the healing rate and related functional outcomes between two retrospective series of distal tibia nonunion cases treated with internal fixation via the posterolateral approach and those managed with Ilizarov external fixation.

methodsThis retrospective cohort study included 47 affected by distal tibia nonunion. The subjects had undergone internal fixation with inter-tibiofibular graft through the posterolateral approach (Group A, n = 24) and Ilizarov method associated or not with bone transport procedures and osteotomies (Group B, n = 23). Results were assessed at a minimum 24 months after surgery. Consolidation rate, radiographic healing time of nonunion, the American Orthopedic Foot and Ankle Society (AOFAS), the short form health survey (SF-12) and Visual Analog Scale (VAS) scores (pain, ability to work and treatment satisfaction) were compared between the groups. Complications and reoperations were also recorded.

resultsThe nonunion healing rate was 75% (18/24) in the group A and 91% in the group B (21/23)(p = 0.001). Consolidation was observed, on average, 5.7 months after surgery (range, 4-9) in the group A and 10.7 months in the B group (range, 5-24) (p = 0.001). All patients recovered have had good functional outcomes with no significant differences between the groups. At final follow-up, AOFAS scores in the A group were 74 (range 52-94), while in the B group it was 79 (range 57-100). Group A showed a better perception of mental health status (SF-12-MCS 46 vs. 45, p = 0.36) and a better satisfaction with the treatment received, but a worse perception of their physical health status (SF-12-PCS 49 vs. 50, p = 0.52) with a lower mean score on working ability.

conclusionDistal tibial nonunion can be successfully treated with the posterolateral approach, or external Ilizarov fixation. There are not significative outcomes differences when patients undergoing internal or external fixation. Although healing times are faster with internal fixation via the posterolateral approach, healing rates are higher with the Ilizarov method.

Indexed as

Fracture Fixation, InternalFractures, UnunitedIlizarov TechniqueTibial FracturesAdultAgedExternal FixatorsFemaleFracture HealingHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultDistal tibiaIlizarov external fixationInternal fixationNonunionPosterolateral approach

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.