Evidence map›Paper›PMID 40640620›Full record

ArticleSurgical endoscopy2025

Pediatric hepatic hydatid cysts: recurrence risk factors following laparoscopic surgery-a 16-year cohort analysis.

Marwa Messaoud, Amani N Alansari, Radhouene Ben Salah, Sami Sfar, Basma Haggui, Amine Ksia, Mongi Mekki, Lassaad Sahnoun

Abstract read
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Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marwa MessaoudPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.ORCID http://orcid.org/0009-0006-1314-6713
Amani N AlansariDepartment of Pediatric Surgery, Hamad Medical Cooperation, 3050, Doha, Qatar. aalansari9@hamad.qa.ORCID http://orcid.org/0000-0002-9369-1933
Radhouene Ben SalahPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.
Sami SfarPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.
Basma HagguiPediatric Surgery Department, Sidi Bouzid Hospital, University of Sousse, Sousse, Tunisia.ORCID http://orcid.org/0009-0006-9712-2945
Amine KsiaPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.ORCID http://orcid.org/0000-0003-4847-7257
Mongi MekkiPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.ORCID http://orcid.org/0000-0002-4513-2184
Lassaad SahnounPediatric Surgery Department, Faculty of Medecine, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia.ORCID http://orcid.org/0000-0002-7822-0463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrence of hepatic hydatid cysts after laparoscopic surgery poses a significant challenge in pediatric patients. The administration of albendazole therapy pre- and post-operatively is proposed to reduce recurrence rates, yet its impact requires further investigation. This study aims to identify predictive factors associated with recurrence of hepatic hydatid cysts in children following laparoscopic surgery, focusing on cyst characteristics and perioperative albendazole therapy.

methodsA retrospective cross-sectional analytical study was conducted using medical records of pediatric patients under 16 years of age who underwent laparoscopic surgery for hepatic hydatid cysts between 2006 and 2021. Collected data included patient demographics, cyst characteristics (size, location, and number), preoperative and postoperative albendazole therapy, surgical duration, and intraoperative complications. Logistic regression analysis was used to identify factors associated with cyst recurrence during the follow-up period, with statistical significance set at p < 0.05.

resultsA total of 152 pediatric patients were included, with a mean age of 7.9 ± 3.3 years. The recurrence rate was 12% (n = 18). In multivariate analysis, longer surgical duration (HR = 1.02; 95% CI 1.00-1.03; p = 0.013) and cysts located outside liver segment II (HR = 0.11; 95% CI 0.01-0.9; p = 0.039) were independently associated with recurrence. Albendazole therapy, administered pre- or post-operatively, was more frequent in the non-recurrence group but did not reach statistical significance. No cases of peritoneal hydatidosis were recorded during follow-up.

conclusionKey predictors of post-laparoscopy recurrence included extended surgical duration and cyst location. Although perioperative albendazole therapy was more frequent in the non-recurrence group, it did not reach statistical significance in reducing recurrence rates. These findings highlight the importance of tailored surgical approaches and careful postoperative monitoring to improve patient outcomes.

Indexed as

Echinococcosis, HepaticLaparoscopyAdolescentAlbendazoleAnthelminticsAnticestodal AgentsChildChild, PreschoolCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleOperative TimeRecurrenceRetrospective StudiesAlbendazoleAnthelminticsAnticestodal AgentsAlbendazoleHydatid cystLaparoscopyLiverPediatricRecurrence

Identifiers

PMID40640620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.