Evidence map›Paper›PMID 40640476›Full record

ArticleIn vitro cellular & developmental biology. Animal2025

Cyto-genotoxic assessment of bisphenol P through expression of DNA damage/repair genes in MDBK cell line.

Muhammad Muddassir Ali, Samra Afzal, Maryam Javed, Imran Rashid, Furqan Awan, Asad Ullah, Tanveer Majeed, Hadeer Darwish, Ahmed Noureldeen, Jawaher Albaqami and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Muhammad Muddassir AliInstitute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan. muddassir.ali@uvas.edu.pk.ORCID http://orcid.org/0000-0003-1919-9294
Samra AfzalInstitute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Maryam JavedInstitute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Imran RashidDepartment of Parasitology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Furqan AwanDepartment of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Asad UllahDepartment of Pathology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
Tanveer MajeedDepartment of Biotechnology Kinnaird College for Women (KCW), Lahore, Pakistan.
Hadeer DarwishDepartment of Biotechnology, College of Science , Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Ahmed NoureldeenDepartment of Biology, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Jawaher AlbaqamiDepartment of Biotechnology, College of Science , Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.
Khalid MehmoodFaculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 6300, Pakistan. khalid.mehmood@iub.edu.pk.ORCID http://orcid.org/0000-0003-4720-8792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol P (BPP) is a recognized endocrine disruptor with detrimental effects on human health. This study aimed to evaluate BPP's cytotoxic and genotoxic effects on Madin-Darby bovine kidney (MDBK) cells by examining changes in gene expression, genotoxicity, and cell survival. Various assays were employed, including the MTT assay, comet assay, micronucleus assay, and real-time PCR for gene expression analysis. Among the series of concentrations (0.5 µM, 1 µM, 2 µM, 4 µM, 8 µM, 16 µM, 32 µM, 64 µM, 128 µM, and 256 µM), the treatment with 32 µM BPP (LC

Indexed as

Benzhydryl CompoundsDNA DamageDNA RepairGene Expression RegulationPhenolsAnimalsBisphenolsCattleCell LineCell SurvivalComet AssayMicronucleus TestsBenzhydryl Compoundsbisphenol PBisphenolsPhenolsCometGene expressionHPRT1 geneMicronucleusMTTOGG1

Identifiers

PMID40640476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.