Evidence map›Paper›PMID 40640429›Full record

ArticleScientific reports2025

Conventional in vitro fertilization enhances preimplantation genetic testing for aneuploidy outcomes in couples with non-male factor infertility.

Xiaolan Li, Qian Li, Yajie Chang, Shujing He, Yanfang Wang, Xiaoyan Liang, Zhiqiang Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaolan Li *Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China.
Qian Li *Reproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China.
Yajie ChangReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China.
Shujing HeReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China.
Yanfang WangReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China.
Xiaoyan LiangReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China. liangxy2@mail.sysu.edu.cn.
Zhiqiang ZhangReproductive Medicine Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655, People's Republic of China. zhangzhq53@mail.sysu.edu.cn.

Funding

the Science and Technology Projects in Guangzhou 2023A04J2243
6 · The paper itself

Abstract

While extensive research has compared ICSI and c-IVF in general ART outcomes, limited evidence exists regarding their relative efficacy and safety in PGT-A cycles. Therefore, we conducted a large retrospective cohort study to evaluate the effect of conventional in vitro fertilization (c-IVF) on the outcomes of preimplantation genetic testing for aneuploidy (PGT-A) in couples with non-male factor infertility. We conducted a large retrospective cohort study including 578 PGT-A cycles with c-IVF performed on couples with non-male factor infertility at our center between January 2019 and October 2024. To control for confounding factors, 578 PGT-A cycles with ICSI during the same period were selected as a control group. Matching was based on maternal age (± 2 years), number of oocytes retrieved (± 3), and progressive motile sperm count (± 3 × 10

Indexed as

AneuploidyFertilization in VitroGenetic TestingInfertilityPreimplantation DiagnosisAdultFemaleHumansMalePregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicAneuploidy rateConventional in vitro fertilizationIntracytoplasmic sperm injectionPreimplantation genetic testing for aneuploidy

Identifiers

PMID40640429
PMCPMC12246052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.