Evidence map›Paper›PMID 40640211›Full record

ArticleScientific data2025

A chromosomal level genome assembly of Nguni Sheep, Ovis aries.

Lucky Tendani Nesengani, Thendo Tshilate, Sinebongo Mdyogolo, Rae Smith, Tracy Masebe, Thomas Raphulu, Acclaim Moila, Abdoallah Sharaf, Sadik Muzemil, Isidore Houaga and 11 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Lucky Tendani NesenganiCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa. nesenlt@unisa.ac.za.ORCID 0000-0003-2678-8425
Thendo TshilateCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.
Sinebongo MdyogoloCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.
Rae SmithCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.ORCID 0000-0002-1379-3949
Tracy MasebeCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.ORCID 0000-0002-1300-9077
Thomas RaphuluLimpopo Department of Agricultur, Polokwane, South Africa.
Acclaim MoilaInqaba Biotech, Pretoria, South Africa.
Abdoallah SharafSequAna Core Facility, Department of Biology, University of Konstanz, Konstanz, Germany.ORCID 0000-0002-3436-9290
Sadik MuzemilRothamsted Research, Harpended, United Kingdom.
Isidore HouagaCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.
Anne MuigaiNational Defence University-Kenya, Nakuru, Kenya.
A DjikengCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.
Josiah KujaBioinformatics Center, University of Copenhagen, Copenhagen, Denmark.
Sally KateeInternational Livestock Research Institute, Nairobi, Kenya.
Julian O OsujiDepartment of Plant Science and Biotechnology, University of Port Harcourt, Port Harcourt, Nigeria.
Zahra Mungloo-DilmohamudDepartment of Digital Technologies, FoICDT, University of Mauritius, Mauritius, Mauritius.
Marietjie BotesSchool of Law, University of KwaZulu-Natal, Durban, South Africa.
Skhumbuzo MbizeniCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa.
Erich JarvisVertebrate Genome Lab, The Rockefeller University, New York, NY, USA.
ThankGod Echezona EbenezerAfrican BioGenome Project (AfricaBP), Nairobi, Kenya.
Mapholi NtanganedzeniCollege of Agriculture and Environmental Sciences, UNISA Science Campus, Florida, Johannesburg, South Africa. maphon@unisa.ac.za.ORCID 0000-0003-4507-6669

Funding

University of South Africa (Unisa) ASDG-RSP
6 · The paper itself

Abstract

Nguni sheep (Ovis aries) are indigenous to the Southern Africa region and common within the smallholder and poor resources farming systems. They are well adapted to different agroecological regions. However, limited genomic resources such as high-quality reference genomes have hindered our understanding of its adaptation and establishment of an effective breeding program. To address this, we assembled a chromosomal-level genome of Nguni sheep using a combination of PacBio HiFi reads and Omni-C reads. The genome size was estimated to be 2.9 Gb with a contig/scaffold N50 74 Mb and 99.6 Mb and a genome completeness of 96.1%, as estimated by the Benchmarking Universal Single-Copy Orthologs (BUSCO) program. The final genome encompassed a total of 25,926 protein-coding genes. The findings of this study provide a valuable genomic resource for understanding the adaptability of the Nguni sheep and the establishment of effective breeding programs.

Indexed as

GenomeSheep, DomesticAnimalsChromosomesSheep

Identifiers

PMID40640211
PMCPMC12246055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.