ArticleNature communications2025
Functional development of the human cerebellum from birth to age five.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07307742 (Effects of Motor-Focused Exercise Training on Brain Function and Gross Motor Skills in Preschool Children), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Motor-Focused Exercise Training on Brain Function and Gross Motor Skills in Preschool Children
Who cites it
14 citing papers in PubMed.
- The cerebellum specializes for language even in the absence of contralateral neocortical inputs.bioRxiv : the preprint server for biology · 2026Article
- Division-Specific Organization of a Shared Functional Scaffold in the Early-Life Human Brain.bioRxiv : the preprint server for biology · 2026Article
- Left Cerebellar-Right Frontal Uncoupling in Female First-Episode Major Depressive Disorder: Synaptic Evidence From [CNS neuroscience & therapeutics · 2026Article
- Functional brain connectivity from the fetal period through infancy: A narrative review of resting-state fMRI studies.Developmental cognitive neuroscience · 2026Review
- Novel neonatal hypoxic-ischemic model demonstrates glial activation and memory deficits without neuronal loss.Pediatric research · 2026Article
- Multiscale brain development across the human lifespan.Communications biology · 2026Review
- Cerebellar growth is associated with domain-specific cerebral maturation and socio-linguistic behavior.Nature communications · 2026Article
- Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior.Nature communications · 2026Article
- Frequency-dependent cerebellar circuits independently gate social vocalizations and movement.bioRxiv : the preprint server for biology · 2026Article
- Functional Connectivity of the Neonatal Cerebellum is Impacted by Sex and Polygenic Liability for Autism.medRxiv : the preprint server for health sciences · 2026Article
- Article
- Attenuated rightward hemispheric asymmetry in ADHD: structural MRI evidence from a normalized asymmetry index and its association with cognitive performance.Frontiers in neuroscience · 2026Article
- Protocol for the "motor-brain development" trial: effects of motor-focused exercise training on brain function and gross motor skills in preschool children.Frontiers in pediatrics · 2026Article
- Prenatal substance exposure and infant neurodevelopment: a review of magnetic resonance imaging studies.Frontiers in human neuroscience · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Despite the cerebellum's crucial role in brain function, its early development, particularly in relation to the cerebrum, remains poorly understood. Here, we examine cerebellocortical connectivity using over 1000 high-quality resting-state functional MRI scans from children between birth and five years of age. By mapping cerebellar topography with fine temporal granularity, we unveil the hierarchical organization of cerebellocortical functional connectivity from infancy. We observe dynamic shifts in cerebellar functional topography, which become more focal with age while largely maintaining stable anchor regions similar to adults, highlighting the cerebellum's evolving yet organized role in functional integration during early development. Our findings demonstrate cerebellar connectivity to higher-order networks at birth, which generally strengthen with age, emphasizing the cerebellum's early role in cognitive processing beyond sensory and motor functions. Our study provides insights into early cerebellocortical interactions, reveals functional asymmetry and sex-specific patterns in cerebellar development, and lays the groundwork for future research on cerebellum-related disorders in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.