Evidence map›Paper›PMID 40640135›Full record

ArticleNature communications2025

Noninvasive cardiac modulation via triplet-sensitized photoswitching in the phototherapeutic window.

Lukas Naimovičius, Mila Miroshnichenko, Ekin Opar, Helen Hölzel, Masa-Aki Morikawa, Nobuo Kimizuka, Manvydas Dapkevičius, Justas Lekavičius, Edvinas Radiunas, Karolis Kazlauskas and 10 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Mechanically Interlocked Indigo Photoswitches.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Tapered fiber probe-based optical cardiac pacemaker.Frontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Lukas NaimovičiusInstitute of Materials Science of Barcelona, ICMAB-CSIC, Bellaterra, Barcelona, Spain.ORCID http://orcid.org/0000-0002-3358-4108
Mila MiroshnichenkoInstitute of Materials Science of Barcelona, ICMAB-CSIC, Bellaterra, Barcelona, Spain.
Ekin OparInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Helen HölzelDepartment of Chemical Engineering, Universitat Politècnica de Catalunya, EEBE, Eduard Maristany 10-14, Barcelona, Spain.ORCID http://orcid.org/0000-0003-2312-9934
Masa-Aki MorikawaDepartment of Applied Chemistry, Graduate School of Engineering, Center for Molecular Systems (CMS), Kyushu University, Fukuoka, Japan.
Nobuo KimizukaDepartment of Applied Chemistry, Graduate School of Engineering, Center for Molecular Systems (CMS), Kyushu University, Fukuoka, Japan.
Manvydas DapkevičiusInstitute of Photonics and Nanotechnology, Vilnius University, Vilnius, Lithuania.
Justas LekavičiusInstitute of Photonics and Nanotechnology, Vilnius University, Vilnius, Lithuania.ORCID http://orcid.org/0009-0002-3361-8088
Edvinas RadiunasInstitute of Photonics and Nanotechnology, Vilnius University, Vilnius, Lithuania.
Karolis KazlauskasInstitute of Photonics and Nanotechnology, Vilnius University, Vilnius, Lithuania.ORCID http://orcid.org/0000-0001-7900-0465
Víctor Cilleros-MañéInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Fabio RiefoloInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID http://orcid.org/0000-0002-6762-2619
Carlo MateraInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID http://orcid.org/0000-0001-6939-3859
Kevser HarmandarAcıbadem Mehmet Ali Aydınlar University, Faculty of Engineering and Natural Sciences, Biomedical Engineering Department, Ataşehir, Istanbul, Türkiye.
Masahiko TaniguchiDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.
Fabienne DumoulinAcıbadem Mehmet Ali Aydınlar University, Faculty of Engineering and Natural Sciences, Biomedical Engineering Department, Ataşehir, Istanbul, Türkiye.ORCID http://orcid.org/0000-0002-0388-8338
Jonathan S LindseyDepartment of Chemistry, North Carolina State University, Raleigh, NC, USA.ORCID http://orcid.org/0000-0002-4872-2040
Pankaj BharmoriaInstitute of Materials Science of Barcelona, ICMAB-CSIC, Bellaterra, Barcelona, Spain. pbharmoria@icmab.es.
Pau GorostizaInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain. pau@icrea.cat.ORCID http://orcid.org/0000-0002-7268-5577
Kasper Moth-PoulsenInstitute of Materials Science of Barcelona, ICMAB-CSIC, Bellaterra, Barcelona, Spain. kasper.moth-poulsen@upc.edu.ORCID http://orcid.org/0000-0003-4018-4927

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) PHOTHERM
6 · The paper itself

Abstract

Red, far red, or near-infrared photoswitchable drugs offer immense photo-pharmacological advantages due to the higher light penetration through the skin. Such photoactivation is achieved using processes such as two- and three-photon absorption, excited-state absorption, and triplet-triplet annihilation upconversion, which require higher photon fluences (W to kW cm

Indexed as

HeartHeart RatePhotosensitizing AgentsPhototherapyAnimalsAzo CompoundsIndolesIsoindolesLarvaazobenzeneAzo CompoundsIndolesIsoindolesPhotosensitizing Agentsphthalocyanine

Identifiers

PMID40640135
PMCPMC12246132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.