Evidence map›Paper›PMID 40639840›Full record

ArticleBMJ health & care informatics2025

Leveraging data science to understand and address multimorbidity in sub-Saharan Africa: the MADIVA protocol.

Kerry Glover, Tabitha Osler, Kayode Adetunji, Tanya Akumu, Gershim Asiki, Diana Awuor, Palwendé Boua, Victoria Bronstein, Joan Byamugisha, Jacques D Du Toit and 40 more

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Article in BMJ health & care informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Kerry Glover *Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-3778-2611
Tabitha Osler *Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0003-2966-6327
Kayode AdetunjiSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0003-0504-382X
Tanya AkumuIBM Research - Africa, Nairobi, Kenya.
Gershim AsikiChronic Disease Management Unit, African Population and Health Research Center, Nairobi, Kenya.
Diana AwuorResearch and Related Capacity Strengthening Unit, African Population and Health Research Center, Nairobi, Kenya.
Palwendé BouaSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Victoria BronsteinSchool of Law, University of the Witwatersrand, Johannesburg, South Africa.
Joan ByamugishaIBM Research - Africa, Johannesburg, South Africa.
Jacques D Du ToitMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-0003-0168
Barry DwolatzkySchool of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa.
Jaya GeorgeWits Diagnostic Innovation Hub, University of the Witwatersrand, Johannesburg, South Africa.
Paul A HarrisDepartments of Biomedical Informatics, Biostatistics, Biomedical Informatics & Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Kobus HerbstDSI-SAMRC South African Population Research Infrastructure Network (SAPRIN), South African Medical Research Council, Durban, South Africa.ORCID http://orcid.org/0000-0002-5436-9386
Karen HofmanSAMRC/Wits Centre for Health Economics and Decision Science - PRICELESS SA, University of the Witwatersrand, Johannesburg, South Africa.
Celeste HoldenSAMRC/Wits Centre for Health Economics and Decision Science - PRICELESS SA, University of the Witwatersrand, Johannesburg, South Africa.
Samuel IddiData Synergy and Evaluation Unit, African Population and Health Research Center, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-2366-2774
Damazo T KadengyeAfrican Population and Health Research Center, Nairobi, Kenya.
Kathleen KahnMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.
Michelle KampSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4334-6883
Nhlamulo KhozaSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Faith KimongoMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0009-0002-7730-6246
Isaac KisianganiChronic Disease Management Unit, African Population and Health Research Center, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-1107-4334
Dekuwin E KogdaClinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Sante, Nanoro, Burkina Faso.ORCID http://orcid.org/0009-0009-1745-9567
Michael KlipinDepartment of Surgery, University of the Witwatersrand, Johannesburg, South Africa.
Stephen P LevittSchool of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0001-6054-6134
Dylan MaghiniSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0001-9542-492X
Karabo MailaSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Eric MaimelaDIMAMO Population Health Research Centre, University of Limpopo, Polokwane, South Africa.
Daniel Maina NderituChronic Disease Management Unit, African Population and Health Research Center, Nairobi, Kenya.ORCID http://orcid.org/0000-0001-9800-2431
Ndivhuwo MakondoIBM Research - Africa, Johannesburg, South Africa.
Molulaqhooa Linda MaoyiDSI-SAMRC South African Population Research Infrastructure Network (SAPRIN), South African Medical Research Council, Durban, South Africa.ORCID http://orcid.org/0000-0002-0176-098X
Reineilwe Given MashabaDIMAMO Population Health Research Centre, University of Limpopo, Polokwane, South Africa.
Nkosinathi Gabriel MasilelaMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4718-9336
Theophilous MathemaSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.
Phelelani Thokozani MpangaseSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0001-8280-8940
Daphine T NyachoweSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0003-2544-804X
Daniel Ohene-KwofieSchool of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa.
Helen RobertsonSchool of Computer Science and Applied Mathematics, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4135-0379
Skyler SpeakmanIBM Research - Africa, Nairobi, Kenya.
Evelyn ThsehlaSAMRC/Wits Centre for Health Economics and Decision Science - PRICELESS SA, University of the Witwatersrand, Johannesburg, South Africa.
Siphiwe A ThwalaIBM Research - Africa, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4587-2246
Roy ZentDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Francesc Xavier Gómez-OlivéMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4876-0848
Chodziwadziwa W KabudulaMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.
Patrick Opiyo OwiliResearch and Related Capacity Strengthening Unit, African Population and Health Research Center, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-9417-8947
Catherine KyobutungiAfrican Population and Health Research Center, Nairobi, Kenya.
Michèle RamsaySydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4156-4801
Stephen TollmanMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand Johannesburg, Johannesburg, South Africa.
Scott HazelhurstSydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, South Africa Scott.Hazelhurst@wits.ac.za.ORCID http://orcid.org/0000-0002-0581-149X

Funding

MADIVA (Multimorbidity in Africa: Digital innovation, visualisation and application)U54TW012077 · FIC · WITS HEALTH CONSORTIUM (PTY), LTD · PI Scott Hazelhurst, Stephen Tollman · 2021 to 2026
$6.9M
FIC NIH HHS U54 TW012077
6 · The paper itself

Abstract

introductionMultimorbidity (MM), defined as two or more chronic diseases in an individual, is linked to adverse outcomes. MM is increasing in sub-Saharan Africa due to rapidly advancing epidemiological and social transitions. The METHODS AND ANALYSIS: MADIVA uses complex, individual-level datasets from research centres in rural Bushbuckridge, South Africa and urban Nairobi, Kenya. These datasets will be harmonised, linked and curated, and then used to develop MM risk prediction models, novel data science methods and interactive dashboards for research and clinical use. Pilot projects and mentorship programmes will support data science capacity development. ETHICS AND DISSEMINATION: Ethics approval has been granted. Dissemination will occur through scientific meetings and publications. MADIVA is committed to making data FAIR: findable, accessible, interoperable and reusable.

Indexed as

Data ScienceMultimorbidityAfrica South of the SaharaHumansKenyadata sciencedata visualizationmachine learningmedical record linkagepublic health informatics

Identifiers

PMID40639840
PMCPMC12258287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.