ArticleChemistry & biodiversity2025
Antiaging, Wound-Healing Properties and Chemical Characterization of Crude Hydroalcoholic Extract and Fractions of Myrcia neoobscura.
Article in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Skin wound healing effects of Pectinodesmus javanensis extract through activation of TGF-β/SMAD signaling pathway.Molecular biology reports · 2026Article
- Antiaging, Wound-Healing Properties and Chemical Characterization of Crude Hydroalcoholic Extract and Fractions of Myrcia neoobscura.Chemistry & biodiversity · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to characterize the phytochemical profile and potential antiaging and wound-healing activities of 70% hydroalcoholic crude extract (CHE) from Myrcia neoobscura leaves and its fractions-insoluble (IF), ethyl acetate (EAF), and aqueous (AF)-for use in phytocosmetics for skin application. CHE and its fractions showed high concentrations of total phenolics, including flavanols and flavonoids. Ten phenolic compounds were identified, with gallic acid as the major, followed by chlorogenic and p-coumaric acids. Catechin, isoorientin, taxifolin, resveratrol, naringenin, and eriodictyol were reported for the first time in the genus. CHE and AF showed the best results in antioxidant assays. In antiglycation activity, EAF showed the highest oxidative glycation inhibition, comparable to quercetin. CHE and AF exhibited the strongest collagenase and elastase inhibition. CHE, IF, and EAF showed the highest SPF. CHE promoted 81.86% fibroblast migration in 24 h, indicating strong wound-healing potential. CHE maintained cellular viability in the MTT assay. In the HET-CAM assay and agarose overlay assays, CHE and fractions were classified as non to mildly irritating. These results suggest potential antiaging applications, mainly attributed to the phenolic profile.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.