Evidence map›Paper›PMID 40638875›Full record

ArticleJCO precision oncology2025

Clinical Significance of

Natasha Persaud, Gunes Gundem, Brian H Kushner, Marc Ladanyi, Neerav Shukla, Shakeel Modak

Abstract read
In one paragraph

Article in JCO precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Targeted therapies in pediatric oncology: A start.Molecular therapy. Oncology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natasha PersaudDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.
Gunes GundemDepartment of Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Brian H KushnerDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-8916-0697
Marc LadanyiDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0001-9055-7213
Neerav ShuklaDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0003-2516-2965
Shakeel ModakDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.ORCID 0000-0002-7280-1726

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTelomere maintenance mechanisms including

methodsTo identify

results

conclusion

Indexed as

NeuroblastomaPromoter Regions, GeneticTelomeraseAdolescentAdultAgedClinical RelevanceFemaleHumansMaleMiddle AgedMutationYoung AdultTelomeraseTERT protein, human

Identifiers

PMID40638875
PMCPMC12252578

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.