ArticleAnnals of medicine2025
Nocturnal heart rate during sleep is associated with increased risk of type 2 diabetes mellitus in adults with obstructive sleep apnoea syndrome.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Comparative effects of MAD and CPAP on heart rate in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Observational
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9 authors.
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Abstract
objectiveFew studies have confirmed the relationship between nocturnal heart rate (HR) and the risk of type 2 diabetes mellitus (T2DM) in patients with obstructive sleep apnoea syndrome (OSAS), and the aim of this study was to investigate this relationship.
methodsThe study retrospectively collected and cross-sectionally analyzed the clinical data of 1104 OSAS patients who met the study inclusion and exclusion criteria in the electronic medical record system of Wuhan Union Hospital. All patients underwent polysomnography and an apnea-hypoventilation index ≥5 was considered OSAS. Logistic regression and restricted cubic spline (RCS) regression were used to analyze the association between nocturnal HR and risk of T2DM. The predictive ability of HR for T2DM was analyzed using receiver operating characteristic (ROC) curves. The study was also analyzed in subgroups by age. HR was also classified into three groups, and the associations between different HR levels and T2DM risk were assessed using three logistic regression models.
resultsThe mean age of the subjects was 54.49 (±9.95) years, and 374 subjects had T2DM. Nocturnal HR levels were higher in the T2DM group compared to the non-T2DM group. Multifactorial logistic regression analysis showed that nocturnal HR was significantly associated with the risk of T2DM (OR = 1.02,
conclusionNocturnal HR was positively correlated with the risk of T2DM in the population with OSAS.
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