SynthesisRevista da Associacao Medica Brasileira (1992)2025
Health outcomes of umbilical cord clamping techniques in preterm neonates: meta-analysis.
Synthesis in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
objectiveThe aim of this study was to determine the effect of umbilical cord clamping time and milking on blood parameters in preterm neonates.
methodsA literature search was conducted between July and September 2024 in four databases. The search was performed using MeSH-based keywords.
resultsIn this study, the results of 14 studies covering a total of 1,609 preterm neonates were analyzed. Follow-up after intervention showed no statistically significant difference in hemoglobin (standardized mean difference=0.22, 95%CI 0.04-0.48, Z=1.65, p=0.10) and bilirubin (standardized mean difference=0.22, 95%CI 0.30-0.74, Z=0.82, p=0.41) between the groups. There was a statistically significant difference in ferritin (standardized mean difference=0.73, 95%CI 0.30-1.15, Z=3.37, p=0.00008) and hematocrit (standardized mean difference=0.30, 95%CI 0.05-0.54, Z=2.41, p=0.02) values, and the effect size was positive. According to the subgroup analysis of the combined results of the studies, it was seen that there was no statistically significant difference in the adverse health outcomes in preterms (OR 0.92, 95%CI 0.74-1.15, Z=0.72, p=0.47).
conclusionFrom the analysis, it can be observed that late cord clamping and cord milking can prevent premature anemia by increasing hematocrit and ferritin formation in preterm newborns.
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