Evidence map›Paper›PMID 40638454›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2025

Cutaneous cryptococcosis resembling keratoacanthoma.

Alex Panizza Jalkh, Naira Sulany Oliveira de Sousa, Juan Diego Ribeiro de Almeida, Flávia da Silva Fernandes, Kátia Santana Cruz, Hagen Frickmann, Marcus Vinícius Guimarães Lacerda, João Vicente Braga de Souza

Abstract readCase Reports
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alex Panizza JalkhFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0006-0892-9852
Naira Sulany Oliveira de SousaPrograma de Pós-Graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-9344-1192
Juan Diego Ribeiro de AlmeidaInstituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-9630-0029
Flávia da Silva FernandesInstituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0003-1591-7025
Kátia Santana CruzFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-3295-7937
Hagen FrickmannDepartment of Microbiology and Hospital Hygiene, Bundeswehr Hospital of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0002-8967-9528
Marcus Vinícius Guimarães LacerdaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0003-3374-9985
João Vicente Braga de SouzaPrograma de Pós-Graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-3163-7499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous cryptococcosis is a manifestation of systemic cryptococcal infection, characterized by polymorphic skin lesions that can make diagnosis challenging. We report an HIV-positive patient with a solitary facial nodule, initially diagnosed as keratoacanthoma. Histopathology, fungal culture, and cerebrospinal fluid analysis confirmed disseminated cryptococcosis with central nervous system involvement caused by Cryptococcus neoformans genotype VNI. He was treated with amphotericin B followed by fluconazole, resulting in complete clinical resolution. This case underscores the need to consider disseminated cryptococcosis in the differential diagnosis of tumorlike skin lesions, particularly in HIV-positive patients.

Indexed as

AIDS-Related Opportunistic InfectionsCryptococcosisCryptococcus neoformansDermatomycosesKeratoacanthomaAmphotericin BAntifungal AgentsDiagnosis, DifferentialFluconazoleHumansMaleMiddle AgedAmphotericin BAntifungal AgentsFluconazole

Identifiers

PMID40638454
PMCPMC12233740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.