Evidence map›Paper›PMID 40638446›Full record

ArticleJournal of applied oral science : revista FOB2025

Influence of molar incisor hypomineralisation severity on dental hypersensitivity, anxiety/fear, and aesthetic self-perception: a cross-sectional study.

Bianca Caroline Gomes, Lana Cardoso-Silva, Beatriz Kelly Barros Lopes, Roberta Paula de Faria Melo, Isabella Silva Catananti, Alexandra Mussolino de Queiroz, Francisco Wanderley Garcia Paula-Silva, David John Manton, Fabrício Kitazono de Carvalho

Abstract read
In one paragraph

Article in Journal of applied oral science : revista FOB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. High prevalence of molar-incisor hypomineralisation in sickle cell disease children and the association with haematologic profile: a retrospective cohort study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bianca Caroline GomesUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0009-0009-9917-1670
Lana Cardoso-SilvaUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0002-4503-8702
Beatriz Kelly Barros LopesUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0002-8598-7777
Roberta Paula de Faria MeloUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0001-6461-8078
Isabella Silva CatanantiUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0001-7384-2485
Alexandra Mussolino de QueirozUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0003-2900-5000
Francisco Wanderley Garcia Paula-SilvaUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0001-8559-532X
David John MantonUniversity of Groningen, University Medical Centre Groningen, Centre for Dentistry and Oral Hygiene, Department of Cariology, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-4570-0620
Fabrício Kitazono de CarvalhoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Odontopediatria, Ribeirão Preto, Brasil.ORCID http://orcid.org/0000-0002-4837-0583

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMolar-incisor hypomineralisation (MIH) significantly impacts children's quality of life due to dental hypersensitivity, anxiety, and aesthetic concerns. Few studies have investigated these factors within the same sample, comparing varying levels of MIH severity to MIH-free controls.

objectivesThis study evaluated dental hypersensitivity, anxiety, and aesthetic self-perception in children with mild MIH, severe MIH, and controls, and explored correlations between the studied variables. METHODOLOGY: A total of 605 students from a single school were evaluated: 110 children with MIH and 214 controls matched by age and sex. MIH severity was clinically assessed using the Ghanim criteria. Hypersensitivity was measured with the visual analogue scale (VAS) and the Schiff Cold Air Sensitivity Scale (SCASS). Anxiety and aesthetic concerns were assessed using the CFSS-DS and CQATA questionnaires, respectively.

resultsOverall, 78 children had mild MIH and 32 had severe MIH. Median for dental hypersensitivity (p<0.001) and aesthetic self-perception (p=0.002) were significantly higher in the severe MIH group compared to both the control and mild MIH groups. No differences were found for anxiety. Elevated VAS-measured dental hypersensitivity levels and impaired self-perceived aesthetics were significantly correlated with greater MIH severity (p<0.05). Spearman's correlation analysis further revealed significant positive correlations between anxiety/fear and VAS scores (p=0.023, r=0.239), between anxiety/fear and aesthetic self-perception scores (p=0.007, r=0.282), and between dental appearance classification and VAS hypersensitivity scores (p=0.035, r=0.222). In contrast, SCASS hypersensitivity scores did not significantly correlate with either anxiety/fear or dental appearance classification (p>0.05).

conclusionsChildren with severe MIH showed higher dental hypersensitivity and greater perceived aesthetic impairment than children with mild MIH or without MIH.

Indexed as

Dental AnxietyDental Enamel HypoplasiaDentin SensitivityEsthetics, DentalSelf ConceptAdolescentCase-Control StudiesChildCross-Sectional StudiesFemaleHumansMalePain MeasurementQuality of LifeReference ValuesSeverity of Illness Index

Identifiers

PMID40638446
PMCPMC12269961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.