Evidence map›Paper›PMID 40638396›Full record

ArticleClinical transplantation2025

Where Do Organ Donors Come From in the United States? An Analysis of Urban and Rural Donation.

Anthony Shadid, Carolyn Chen, Elizabeth L Godfrey, Addison Xu, John Goss, Abbas Rana

Abstract read
In one paragraph

Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Contribution of donor hospital characteristics to deceased donor organ recovery rates.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  2. Article
  3. Defining Veteran Rurality: An Analysis of the U.S. Veterans Health Administration Rural-Urban Taxonomy.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anthony ShadidDivision of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0009-0000-6282-1427
Carolyn ChenDivision of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Elizabeth L GodfreyDivision of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Addison XuTexas A&M School of Medicine, Bryan, Texas, USA.
John GossDivision of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Abbas RanaDivision of Abdominal Transplantation, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0000-0003-2979-0598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the primary limiting factors in organ transplantation is limited supply of deceased donor allografts. Although there are multiple potential strategies to increase transplantation access, increasing donor organ supply remains a priority. This study aims to analyze the origins of donor supply based on donor and hospital ZIP codes.

methodsOrgan Procurement and Transplantation Network (OPTN) deceased donor database was analyzed. ZIP codes were assigned Rural-Urban Commuting Area (RUCA) code based on definitions from the WWAMI Rural Health Research Center. These RUCA codes, ranging from 1 (metropolitan core) to 10 (rural), allowed for a census-based classification of donor residential ZIP codes. Donor density was calculated as donors per million population. Proportionality between donor rurality was compared to general mortality data from the CDC WONDER database. Statistical analysis was performed in Stata 17.0.

resultsRural zones and micropolitan zones supply 7.2% and 9.7% of donors despite accounting for 8.5% and 10.7% of deaths, respectively. In contrast, urban zones yield 83.1% of donors while accounting for 80.8% of deaths. Donors from rural and micropolitan regions were on average younger and more likely to have trauma-related mechanisms of death, while being less likely to be expanded criteria donors (ECD) or to have required pressor support. Lastly, rural and micropolitan donors were more likely to have written intent to donate.

conclusionThe donor supply from rural and micropolitan regions is not fully reflective of their population size or donor potential. These communities may represent a valuable opportunity to expand the national donor pool through continued outreach and collaboration.

Indexed as

Organ TransplantationRural PopulationTissue and Organ ProcurementTissue DonorsUrban PopulationAdultFemaleHumansMaleMiddle AgedPrognosisUnited Statesorgan donationpopulation densityRUCArural healthtransplantationurban‐rural disparities

Identifiers

PMID40638396
PMCPMC12244443

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.