Evidence map›Paper›PMID 40638262›Full record

Trial reportThe journal of spinal cord medicine2026

Immersive virtual reality for neuropathic pain management in spinal cord injury: A randomized controlled trial.

J Samson Selvaraj, Henry Prakash, Thomas Anand Augustine, S Samuel Kamalesh Kumar, Senthil Velkumar, J Augustin Amalraj

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of spinal cord medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J Samson SelvarajDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.ORCID 0009-0001-3117-1449
Henry PrakashDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.
Thomas Anand AugustineDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.
S Samuel Kamalesh KumarDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.
Senthil VelkumarDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.
J Augustin AmalrajDepartment of Physical Medicine and Rehabilitation, Rehabilitation Institute, Christian Medical College, Vellore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPRIMARY: To evaluate the efficacy of immersive virtual reality (VR) in reducing neuropathic pain (NP) in individuals with spinal cord injury (SCI). SECONDARY: To assess the impact of immersive VR on depersonalization symptoms in the SCI population.

designDouble-blind, randomized controlled trial.

settingRehabilitation unit of a tertiary care teaching hospital in South India.

participantsFifty-two individuals with SCI (ASIA A, B, and C) who had a LANSS (Leeds Assessment of Neuropathic Symptoms and Signs) score ≥12 and were on stable pharmacological treatment. Participants were randomized using computer-generated block randomization.

interventionsThe intervention group received immersive VR exposure via a head-mounted display, involving virtual tasks such as wheelchair propulsion, cycling, and walking, for 15 min per session, twice daily, five days a week, over two weeks. The control group viewed 2D animated films of equivalent duration using the same device. OUTCOME MEASURES: Visual Analog Scale (VAS) for neuropathic pain and Cambridge Depersonalization Scale (CDS) for depersonalization.

resultsForty-three participants completed the trial (intervention:

conclusionImmersive VR is a promising nonpharmacological, non-invasive intervention for managing neuropathic pain in individuals with SCI. It is associated with improved embodiment and reduced depersonalization symptoms, offering a potential pathway to enhance quality of life. Its portability, minimal adverse effects, and ease of customization make it a viable adjunct to conventional rehabilitation strategies.

Indexed as

NeuralgiaPain ManagementSpinal Cord InjuriesVirtual RealityVirtual Reality Exposure TherapyAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedPain MeasurementTreatment OutcomeYoung AdultDepersonalizationNeuralgiaParaplegiaRehabilitationSpinal cord injuriesVirtual reality

Identifiers

PMID40638262
PMCPMC13123074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.