Evidence map›Paper›PMID 40638247›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Higher versus Lower Phosphate Targets for Patients Undergoing In-Center Hemodialysis: A Randomized Controlled Trial.

Daniel Edmonston, Tamara Isakova, Laura M Dember, Sophia Waymyers, Davy Andersen, Kevin E Chan, Hrishikesh Chakraborty, Myles Wolf

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Reducing Bias in Cluster Randomized Trials in Nephrology.Journal of the American Society of Nephrology : JASN · 2026
    Article
  3. Is phosphate burden an under-recognized driver of apparent treatment-resistant hypertension in CKD?Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Phosphate-latest news and ongoing trials.Clinical kidney journal · 2026
    Review
  5. "Hi"s and "Lo"s of Targeting Serum Phosphate Levels in Hemodialysis.Journal of the American Society of Nephrology : JASN · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel EdmonstonDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0003-2589-6993
Tamara IsakovaDivision of Nephrology, Department of Medicine, Center for Translational Metabolism and Health, Institute of Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.ORCID 0000-0002-9763-2367
Laura M DemberRenal, Electrolyte and Hypertension Division, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0002-9735-7473
Sophia WaymyersDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-6925-4808
Davy AndersenDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Kevin E ChanNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Hrishikesh ChakrabortyDuke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Myles WolfDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-1127-1442

Funding

NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
HiLo Competitive RenewalUH3DK118748 · NIDDK · DUKE UNIVERSITY · PI CHAKRABORTY, HRISHIKESH · 2019 to 2024
$5.9M
HiLoUG3DK118748 · NIDDK · DUKE UNIVERSITY · PI WOLF, MYLES S · 2018 to 2018
$842k
NCCIH NIH HHS U24 AT009676NIDDK NIH HHS UG3 DK118748NIDDK NIH HHS UG3/UH3DK118748NIDDK NIH HHS UH3 DK118748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic hemodialysishyperphosphatemiamineral metabolism

Identifiers

PMID40638247
PMCPMC12677831

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.