Evidence map›Paper›PMID 40638229›Full record

ArticleJournal of analytical toxicology2025

The detection of cannabinoids in breath after ingestion of cannabis-infused edibles.

Jennifer L Bery, Ashley Brooks-Russell, Tara M Lovestead, Kavita M Jeerage

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of analytical toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jennifer L BeryApplied Chemicals and Materials Division, National Institute of Standards and Technology, 325 Broadway Ave, Boulder, CO 80305, United States.ORCID 0000-0002-1395-1062
Ashley Brooks-RussellColorado School of Public Health, University of Colorado Anschutz Medical Campus, 13001 E. 17th Place, Aurora, CO 80045, United States.
Tara M LovesteadApplied Chemicals and Materials Division, National Institute of Standards and Technology, 325 Broadway Ave, Boulder, CO 80305, United States.
Kavita M JeerageApplied Chemicals and Materials Division, National Institute of Standards and Technology, 325 Broadway Ave, Boulder, CO 80305, United States.

Funding

Novel approaches to assessing cannabis impaired drivingR01DA049800 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BROOKS-RUSSELL, ASHLEY · 2020 to 2024
$2.6M
DOCForensic Science Research ProgramHHSNIDANIDA NIH HHS R01 DA049800NIDA NIH HHS R01DA049800NIHNIH HHSNIST
6 · The paper itself

Abstract

The increase of Δ9-tetrahydrocannabinol (THC) in breath after cannabis inhalation has been well-documented in the forensic field, but the trends after ingestion of cannabis-infused edibles have not yet been investigated. In this study, participants ingested a cannabis-infused edible and provided breath samples before and at three timepoints after ingestion. Participants were assigned to one of two breath sampling devices. THC was found in most pre-use breath samples, and THC concentration had variable trends after ingestion. Nineteen participants exhibited a maximum in their THC concentration at 47, 92, or 180 min after ingestion, while six participants had their highest THC concentration before the observed ingestion, and four participants had no significant change in THC concentration over the four samples. Five additional cannabinoids were detected in breath. While cannabidiol (CBD) trends followed THC trends for some participants, diverging trends in other participants suggest different biological processing of CBD derived from edibles. This proof-of-concept study shows that THC concentration in breath can increase after the ingestion of cannabis-infused edibles, but the uncertainty of breath measurements and a longer time window need to be further explored.

Indexed as

CannabinoidsCannabisDronabinolSubstance Abuse DetectionAdultBreath TestsCannabidiolFemaleHumansMaleYoung AdultCannabidiolCannabinoidsDronabinolbreathcannabisforensic toxicologyΔ9-tetrahydrocannabinol (THC)

Identifiers

PMID40638229
PMCPMC12842605

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.