Evidence map›Paper›PMID 40638076›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Association of hypoperfusion intensity ratio and cerebral blood volume Index with good outcome in patients transferred for thrombectomy.

Andrew W Asimos, Hongmei Yang, Dale Strong, Katelynn J Teli, Jonathan D Clemente, Gary DeFilipp, Joe Bernard, William Stetler, Jonathan M Parish, Andrew Hines and 2 more

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Real-world functional outcomes and predictors of futile recanalization in patients meeting criteria for SELECT2.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andrew W AsimosDepartment of Emergency Medicine, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-6697-3724
Hongmei YangQuality Division, Clinical Quality Analytics, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-6535-2862
Dale StrongQuality Division, Clinical Quality Analytics, Atrium Health, Charlotte, NC, USA.ORCID 0000-0003-4059-0319
Katelynn J TeliNeurosciences Institute, Atrium Health, Charlotte, NC, USA.
Jonathan D ClementeDepartment of Radiology, Atrium Health, Charlotte, NC, USA.ORCID 0000-0001-8702-3683
Gary DeFilippDepartment of Radiology, Atrium Health, Charlotte, NC, USA.
Joe BernardDepartment of Neurosurgery, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-4270-4458
William StetlerDepartment of Neurosurgery, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-2721-328X
Jonathan M ParishDepartment of Neurosurgery, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-9634-6406
Andrew HinesDepartment of Radiology, Atrium Health, Charlotte, NC, USA.
Jeremy B RhotenNeurosciences Institute, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-7753-2158
Rahul R KaramchandaniNeurosciences Institute, Atrium Health, Charlotte, NC, USA.ORCID 0000-0002-2111-5523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundHypoperfusion intensity ratio (HIR) and cerebral blood volume index (CBVI) have been shown to predict clinical outcome, but further validation is needed in patients initially presenting to non-thrombectomy centers.MethodsWe conducted a retrospective study of patients with an anterior circulation large vessel occlusion (ACLVO) who underwent computed tomography perfusion (CTP) scanning at a non-thrombectomy center and were transferred for consideration of thrombectomy. We evaluated the association of three measures of collateral status (HIR, CBVI, and a collateral score combining both measures) to 90-day modified Rankin scale (mRS).ResultsWe identified 497 eligible patients, of whom 93% underwent thrombectomy. After adjusting for covariates, ascending numerical CBVI was associated with 90-day mRS ≤ 2 in both overall patients and the recanalized subgroup (

Indexed as

cerebral blood volumeischemic strokeperfusionThrombectomy

Identifiers

PMID40638076
PMCPMC12245811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.