Evidence map›Paper›PMID 40637825›Full record

ArticleEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2026

Bioactive materials with S-PRG filler in paediatric dentistry: a scoping review.

R Manente, P C da Silva Mira, S A Milori Corona

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

R ManenteRibeirão Preto School of Dentistry, Universidade de São Paulo, São Paulo, Brazil. rafaela.manente@usp.br.
P C da Silva MiraRibeirão Preto School of Dentistry, Universidade de São Paulo, São Paulo, Brazil.
S A Milori CoronaRibeirão Preto School of Dentistry, Universidade de São Paulo, São Paulo, Brazil. silmaracorona@forp.usp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.644213/2021-00
6 · The paper itself

Abstract

backgroundGiomer is a collective term for dental-related products containing the S-PRG (surface pre-reacted glass-ionomer) filler, which features bioactive effects.

objectiveThis study aimed to conduct a scoping review about the clinical performance of this type of dental material in young patients.

methodsWe included clinical trials analysing the survival rate as well as the aesthetic, functional, and biological properties of bioactive materials (resin composites, sealants, or varnishes) with S-PRG technology used in paediatric dentistry. Electronic searches were conducted in four databases (PubMed, Web of Science, Embase, and Virtual Health Library) along with manual searches until December 2024. The collected data were organised in Excel tables, and a critical appraisal of individual sources of evidence was conducted.

resultsOne hundred and ninety-three articles were identified, of which 13 met the inclusion criteria. A total of 846 patients were included in the studies evaluated, with ages ranging between 2.5 and 15 years. Giomer-based materials demonstrated an effect in preventing caries lesion development, a shorter mean application time than conventional sealants, and similar results regarding colour match, surface texture, marginal discolouration, and post-operative sensitivity when compared to conventional restorative materials. They also offered similar beneficial remineralisation effects as a coating material. However, some studies reported retention failures and low survival rates, especially with bioactive self-conditioning sealant, demonstrating technique sensitivity.

conclusionDental products containing S-PRG particles offer an effective alternative for paediatric dentistry, despite their sensitivity to external factors during application. They possess aesthetic qualities comparable to other traditional materials and are particularly suitable for patients at high caries risk due to their biological properties in both preventive and restorative treatments.

Indexed as

Acrylic ResinsDental CariesDental MaterialsGlass Ionomer CementsPediatric DentistryAdolescentChildChild, PreschoolComposite ResinsHumansPit and Fissure SealantsSilicon DioxideAcrylic ResinsComposite ResinsDental Materialsglass ionomerGlass Ionomer CementsPit and Fissure SealantsSilicon DioxideBioactive materialsDental cariesPit and fissure sealantsPre-reacted glass fillersResin compositeScoping review

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.