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ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Pars plana suturing of intravitreal fluocinolone acetonide in noninfectious uveitis.

Dillan Patel, Sunir J Garg, Xihui Lin

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dillan PatelDepartment of Ophthalmology, Temple University Hospital, Philadelphia, PA, 19140, USA.
Sunir J GargMid Atlantic Retina, The Retina Service of Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Suite 1020, Philadelphia, PA, 19107, USA. sgarg@midatlanticretina.com.
Xihui LinDepartment of Ophthalmology, School of Medicine, Kresge Eye Institute, Wayne State University, Detroit, MI, 48201, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo described and evaluate a technique in which the fluocinolone acetonide 0.18 mg implant is sutured into the pars plana in cases of noninfectious uveitis.

methodsOcular vitals and slit lamp examination was performed at baseline, 1 month, 3 months, 6 months and 12 months follow up. Optical coherence tomography was obtained at all these visits. Data assessed included visual acuity; intraocular pressure; signs of active inflammation including anterior chamber cell, anterior chamber flare, vitreous cell, macular edema, as well as other forms of ocular inflammation; surgical complications; and need for additional interventions.

results6 eyes of 6 patients had scleral fixation of the fluocinolone implant. The mean visual acuity remained stable between the visit prior to refixation and 12 months after scleral fixation (0.03 log MAR change, p = 0.92). The mean macular central subfield thickness decreased from the visit prior to refixation to 12 months after scleral fixation (252.4 μm decrease, p = 0.38). No eyes required additional therapy to control posterior noninfectious uveitis or macular edema.

conclusionIn patients with aphakia, compromised zonules/posterior lens capsule, and anterior or scleral-fixated intraocular lenses, all of which are contraindications to injection of posterior segment implants, scleral fixation of the 0.18 mg fluocinolone acetonide implant may be useful for treatment of noninfectious uveitis.

Indexed as

Fluocinolone AcetonideGlucocorticoidsOphthalmologic Surgical ProceduresScleraSuture TechniquesUveitisAdultAgedDrug ImplantsFemaleFollow-Up StudiesHumansIntraocular PressureIntravitreal InjectionsMaleMiddle AgedDrug ImplantsFluocinolone AcetonideGlucocorticoidsFluocinolone acetonideMacular edemaPars plana vitrectomyScleral fixationSteroid implantUveitis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.