Evidence map›Paper›PMID 40637790›Full record

ArticleDiscover oncology2025

Radiation-induced acute pericarditis after palliative spine radiation in a non-small cell lung cancer patient on osimertinib: a case report.

Chomkwan Decha-Umphai, Thitiwan Prachanukul, Nanthida Phattraprayoon, Teerapat Ungtrakul

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chomkwan Decha-UmphaiPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Thitiwan PrachanukulChulabhorn Hospital, Chulabhorn Royal Academy, Bangkok, Thailand.
Nanthida PhattraprayoonPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand.
Teerapat UngtrakulPrincess Srisavangavadhana Faculty of Medicine, Chulabhorn Royal Academy, Bangkok, Thailand. teerapat.ung@cra.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation-induced acute pericarditis is a rare but life-threatening condition requiring prompt recognition. We report a case of acute pericarditis occurring immediately after palliative spine radiation in a 54-year-old male with non-small cell lung cancer (NSCLC) on Osimertinib. He initially presented with brain, liver, spleen, and bone metastases and was treated with erlotinib and whole-brain radiation. Disease progression prompted a switch to Osimertinib and palliative spine radiation for spinal cord compression. Two days post-radiotherapy, he developed acute chest pain, diagnosed as radiation-induced pericarditis, possibly exacerbated by Osimertinib. Symptoms improved with aspirin and colchicine, and Osimertinib was safely resumed. This case highlights the importance of early recognition of radiation-induced pericarditis, particularly in patients receiving concurrent thoracic radiation and Osimertinib, to ensure timely management and prevent complications.

Indexed as

Non-small cell lung cancerOsimertinibPalliative spinal radiation therapyRadiation-induced acute pericarditisRadiation-induced heart disease

Identifiers

PMID40637790
PMCPMC12246317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.