Evidence map›Paper›PMID 40637630›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada2025

The prevalence of vitamin D deficiency and insufficiency in calcium oxalate stone formers in Ontario, Canada, and the impact of vitamin D supplementation.

Mario Basulto-Martinez, Zoya Khandwala, Tariq Alotaibi, Solon Ierides, Jennifer Bjazevic, Stan van Uum, Kristin K Clemens, Hassan Razvi

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Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Rethinking vitamin D supplementation in calcium stone formers.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mario Basulto-MartinezDivision of Urology, St. Joseph's Hospital, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Zoya KhandwalaSchulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Tariq AlotaibiDivision of Urology, St. Joseph's Hospital, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Solon IeridesDivision of Urology, St. Joseph's Hospital, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Jennifer BjazevicDivision of Urology, St. Joseph's Hospital, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Stan van UumLawson Research Institute, London, ON, Canada.
Kristin K ClemensLawson Research Institute, London, ON, Canada.
Hassan RazviDivision of Urology, St. Joseph's Hospital, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLow vitamin D is a possible risk factor among calcium oxalate (CaOx) stone formers, although its routine assessment and the role for supplementation remain controversial. This study aimed to examine the prevalence of low vitamin D in a large Canadian cohort and to assess the impact of replacement therapy on metabolic and radiographic outcomes.

methodsA retrospective review of patients with CaOx stones who underwent a full metabolic evaluation, including two 24-hour urine collections in a multidisciplinary metabolic stone clinic, was conducted to determine the prevalence of 25-hydroxy vitamin D (25-OH vitamin D) deficiency/insufficiency. A subset of patients receiving vitamin D supplementation was assessed longitudinally for changes in metabolic parameters and stone growth and compared to a cohort with normal values.

resultsAmong 748 patients, 64% had low vitamin D levels at baseline. These patients were more likely to be younger (53 [42.5-61] years vs. 57 [44-67], p<0.001), have a higher body mass index (BMI) (29.3 [25.7-33.3) kg/m

conclusionsLow vitamin D is very common among Canadian CaOx stone formers and should be a routine part of an in-depth metabolic workup. Vitamin D administration can be safely recommended to stone formers without risk of inducing stone progression.

Identifiers

PMID40637630
PMCPMC12517434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.