Evidence map›Paper›PMID 40637587›Full record

Trial reportPM & R : the journal of injury, function, and rehabilitation2026

Cross-lagged assessment between indices of leisure time physical activity and domains of quality of life after electrical stimulation training in persons with spinal cord injury: An exploratory trial.

Ashraf S Gorgey, Refka E Khalil, David R Dolbow, William Carter, Paul B Perrin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PM & R : the journal of injury, function, and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ashraf S GorgeySpinal Cord Injury and Disorders, Richmond VA Medical Center, Richmond, Virginia, USA.ORCID 0000-0002-9157-6034
Refka E KhalilSpinal Cord Injury and Disorders, Richmond VA Medical Center, Richmond, Virginia, USA.
David R DolbowPhysical Therapy Program and College of Osteopathic Medicine, William Carey University, Hattiesburg, Mississippi, USA.
William CarterDepartment of Physical Medicine & Rehabilitation, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-1938-4628
Paul B PerrinSchool of Data Science and Department of Psychology, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0003-2070-215X

Funding

Congressionally Directed Medical Research Programs W81XWH-14-SCIRP-CTA
6 · The paper itself

Abstract

backgroundAn existing association was noted between leisure time physical activity (LTPA) and quality of life (QOL) after spinal cord injury (SCI). Furthermore, electrical stimulation exercise program has been shown to improve domains of QOL. However, the relative causality between indices of LTPA and domains of QOL are not well studied before or after a regimen of electrical stimulation program in persons with SCI.

objectiveTo examine the relationships between levels of weekly leisure-time physical activity (LTPA) and quality of life (QOL) domains before and after 24 weeks of an electrical stimulation exercise program in persons with spinal cord injury (SCI).

designLongitudinal exploratory trial as part of a randomized clinical trial.

settingVeterans Affairs medical center and SCI center.

participantsA convenience sample of 31 participants with chronic SCI were randomized into two groups of 15 and 16, respectively.

interventionsThe first group underwent twice weekly sessions of lower extremity neuromuscular electrical stimulation-resistance training (NMES-RT) for 12 weeks and a subsequent 12 weeks of twice-per-week functional electrical stimulation lower extremity cycling. The second group underwent an identical regimen with the exception that NMES-RT was substituted for passive movement training.

main outcome measuresOutcome measures included the QOL Short Form and the LTPA Questionnaire that were conducted at baseline (T1); post intervention one (T2) and post intervention two (T3). A series of cross-lagged panel models was run with Amos Version 29.0 to test relative directional effects of LTPA and QOL on each other over time.

resultsAfter combining both groups, psychological and social QOL tended to have a stronger directional effect on LTPA, but after the intervention the directional effect reversed. Although LTPA had no directional effect on physical health QOL, it became more dominant in the psychological health domain from T2 to T3. The cross-lagged effect from LTPA to psychological health QOL was either larger or demonstrated a more positive effect relative to the cross-lagged effect from psychological health QOL to LTPA.

conclusionsTwenty-four weeks of an electrical stimulation program did not directly enhance indices of LTPA after SCI. However, suggested improvements in psychological and social domains may be due in part to LTPA following an electrical stimulation exercise program.

Indexed as

Electric Stimulation TherapyExerciseLeisure ActivitiesQuality of LifeSpinal Cord InjuriesAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedTreatment Outcome

Identifiers

PMID40637587
PMCPMC12903624

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.