ArticlePediatric pulmonology2025
Congenital Pulmonary Airway Malformations: Experience of a Tunisian Tertiary Referral Center Over a Five-Year Period.
Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Management and outcomes of congenital pulmonary airway malformations and bronchopulmonary sequestrations diagnosed in the fetal period.Pediatric surgery international · 2026Article
- Antenatally diagnosed severe congenital pulmonary airway malformation requiring life-saving lobectomy in the early neonatal period: A case report.Radiology case reports · 2026Article
- Early surgery before the onset of symptoms: a retrospective analysis of congenital cystic adenomatoid malformations of the lung.Journal of thoracic disease · 2026Article
- Congenital pulmonary airway malformations: prenatal markers, perinatal outcomes, and long-term follow-up experience.Revista da Associacao Medica Brasileira (1992) · 2026Article
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7 authors.
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Abstract
backgroundCongenital pulmonary airway malformations (CPAMs) are rare developmental lung anomalies. The optimal management of asymptomatic neonates remains a subject of debate. This study presents the experience of a Tunisian tertiary referral in the prenatal and postnatal diagnosis and management of CPAM.
methodsWe conducted a 5-year retrospective descriptive study (2019-2024) study in the Neonatology and Intensive Care Unit of the Maternity and Neonatology Center of Tunis. All neonates diagnosed with CPAM were included.
resultsThirteen neonates with CPAM were managed. The mean maternal age was 31.4 yearsAntenatal diagnosis was made in 77% (10/13) of cases. Polyhydramnios was observed in two cases, hydrops fetalis in one, and dextrocardia in one. No antenatal interventions were performed. Cesarean section was performed in 10 cases, including four for fetal indications. Three neonates developed severe respiratory distress requiring mechanical ventilation; two died before surgical intervention, and one underwent lobectomy via thoracotomy at 9 months via thoracotomy, with an uneventful recovery. Histopathological examination confirmed type II CPAM. The remaining 10 patients were managed conservatively, with favorable outcomes during a mean follow-up of 4 years.
conclusionsThe management of CPAM requires a multidisciplinary team and begins in the antenatal period. Even asymptomatic patients require close and prolonged monitoring, as complications may arise later. Surgical intervention should be considered on a case-by-case basis.
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