Evidence map›Paper›PMID 40637374›Full record

ArticleJournal of surgical oncology2025

Socioeconomic Influences on Melanoma Incidence Patterns by Stage in the US.

Trisha Lal, Weichuan Dong, Siran M Koroukian, Natalie N Chakraborty, Luke D Rothermel, Richard S Hoehn

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Trisha LalDivision of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.ORCID https://orcid.org/0009-0000-5821-1159
Weichuan DongCase Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Siran M KoroukianSchool of Medicine, Case Western Reserve University, Cleveland, Ohio.
Natalie N ChakrabortyDivision of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Luke D RothermelDivision of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Richard S HoehnDivision of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMelanoma is one of the fastest-growing cancers in the United States, with nearly 100% 5-year survival for early-stage disease compared to 35% for late-stage disease. Regional studies suggest that areas with increased early-stage melanoma diagnoses may not experience a reduction in late-stage cases, raising questions about the effectiveness of early detection. We hypothesize that higher socioeconomic status (SES) will correlate with increased early-stage melanoma without a decrease in late-stage disease, with geographic variation across US regions.

methodsThis cross-sectional study used SEER data to analyze 829 391 non-Hispanic White patients diagnosed with melanoma between 2004 and 2021, including 725 077 with early-stage (in situ/localized) and 104 314 with late-stage (regional/distant) disease. Regression models evaluated associations between county-level stage-specific melanoma incidence and population characteristics, including SES, ultraviolet exposure, agricultural employment, and rural-urban status.

resultsHigher SES counties had higher early-stage melanoma incidence without a reduction in late-stage incidence. Counties in the West and South had increased odds of early-stage melanoma, while rural counties exhibited lower melanoma incidence across stages. Agricultural employment and ultraviolet exposure were not consistently associated with melanoma incidence.

conclusionFindings suggest early- and late-stage melanoma may represent distinct diseases. Screening may aid in early detection, but its impact on reducing late-stage disease and mortality remains uncertain.

Indexed as

MelanomaSkin NeoplasmsSocial ClassAdultAgedCross-Sectional StudiesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedNeoplasm StagingPrognosisSEER ProgramSocioeconomic Factorscancer detectionhealth disparitiesmelanomascreeningsocioeconomic status

Identifiers

PMID40637374
PMCPMC12455526

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.