ArticleJournal of agricultural and food chemistry2025
Modifying Antifungal Peptides as Safe Food Preservatives.
Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Aqueous-Phase Peptide Synthesis via Stepwise Amino Acid Elongation Catalyzed by Aqualigase.ACS organic & inorganic Au · 2026Article
- In Vitro Screening of Short Synthetic Antimicrobial Peptides Toward Food-Relevant Microorganisms: Antifungal Activity and Molecular Docking Analysis.Microorganisms · 2026Article
- A chitosan-lasso peptides nanoparticle for enhanced antibacterial activity and fresh-keeping efficacy in eggs and chilled chicken.Current research in food science · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Food loss and waste (FLW) constitute a major global concern with significant environmental and economic ramifications. A major cause of FLW is fungal contamination, leading to food spoilage. Here, we investigate the use of antimicrobial peptides (AMPs) as a new source for food preservatives to combat filamentous fungi and yeast contamination. Specifically, we focused on two model AMPs, BP100 and P-113, and their derivatives that were designed and synthesized as antifungal agents for food preservation. BP100 and P-113 were modified in order to enhance their efficacy. BP100 was modified by substituting its N-terminal lysine with tryptophan (i.e., BP100 K1W) to extend its hydrophobic α-helical side, and P-113 was extended by synthesizing the original sequence triplicated (i.e., P-113 Triple). The modified peptides demonstrated strong antifungal and antibacterial activities. Importantly, they showed low cytotoxicity and were digestible, indicating their safety for consumption. BP100 K1W was particularly effective in a hummus food matrix model, successfully inhibiting
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.