Evidence map›Paper›PMID 40636946›Full record

ArticleFrontiers in pain research (Lausanne, Switzerland)2025

Repetitive transcranial magnetic stimulation at low frequency for the treatment of fibromyalgia. Results from the first treatment cohort at the brainwave clinic.

Elliot Nation, Anushka Irani, Stephanie Barrett

Abstract read
In one paragraph

Article in Frontiers in pain research (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elliot NationThe Brainwave Clinic, The London Clinic, London, United Kingdom.
Anushka IraniDepartment of Rheumatology, Mayo Clinic, Jacksonville, FL, United States.
Stephanie BarrettThe Brainwave Clinic, The London Clinic, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the clinical effectiveness of low-frequency repetitive transcranial magnetic stimulation (rTMS) in treating fibromyalgia (FM) in a real-world setting. Methods: Eighteen adults diagnosed with FM received 20 sessions of low-frequency rTMS over the right dorsolateral prefrontal cortex (DLPFC). Pain and symptom burden were assessed using the Numerical Rating Scale (NRS), Fibromyalgia Impact Questionnaire (FIQ), Sheehan Disability Scale (SDS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Outcomes were compared using paired Results: Statistically significant improvements were observed in NRS, FIQ, BDI, and BAI. A non-significant trend towards reduced disability (SDS) was observed. No serious adverse effects were reported. Conclusion: Low-frequency rTMS over the DLPFC shows promise as a safe and effective treatment for FM, improving pain, mood, and impact of FM symptoms, with a trend towards improving disability. Further research with larger cohorts is needed.

Indexed as

fibromyalgiahypermobilityneuromodulationrheumatologyrTMS

Identifiers

PMID40636946
PMCPMC12237879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.