Evidence map›Paper›PMID 40636730›Full record

ReviewiLIVER2024

Volatile organic compounds for the detection of hepatocellular carcinoma-A scoping review.

Sayed Metwaly, Alicja Psica, Opeyemi Sogaolu, Irfan Ahmed, Ashis Mukhopadhya, Mirela Delibegović, Mohamed Bekheit

Abstract readReview
In one paragraph

Review in iLIVER, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sayed MetwalyDivision of Internal Medicine, Aberdeen Royal Infirmary, NHS Grampian, Scotland, Aberdeen, AB25 2ZD, United Kingdom.
Alicja PsicaDepartment of General Surgery, Aberdeen Royal Infirmary, NHS Grampian, Scotland, Aberdeen AB25 2ZD, United Kingdom.
Opeyemi SogaoluDepartment of General Surgery, Aberdeen Royal Infirmary, NHS Grampian, Scotland, Aberdeen AB25 2ZD, United Kingdom.
Irfan AhmedAberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill Health Campus, Aberdeen, AB25 2ZD, United Kingdom.
Ashis MukhopadhyaDivision of Internal Medicine, Aberdeen Royal Infirmary, NHS Grampian, Scotland, Aberdeen, AB25 2ZD, United Kingdom.
Mirela DelibegovićAberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill Health Campus, Aberdeen, AB25 2ZD, United Kingdom.
Mohamed BekheitAberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill Health Campus, Aberdeen, AB25 2ZD, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is an increasingly common and the second leading cause of cancer mortality worldwide with a 5-year survival rate about 12%. Less than 20% of HCC patients are eligible to curative treatment owing to the late presentation. Clearly, there is a need for a readily accessible, early screening tool. This scoping review critically appraises and synthesizes the current published knowledge about the use of exhaled volatile organic compounds (VOCs) as a potential noninvasive means for HCC detection aiming to advance this nascent field. A systematic electronic search was conducted. The search strategy included all studies published until the 24th of March 2023 using a combination of relevant keywords. The search yielded 9 publications using the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Two of the studies described

Indexed as

Hepatocellular carcinomaMetabolomicsVolatile organic compounds

Identifiers

PMID40636730
PMCPMC12212718

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.