Evidence map›Paper›PMID 40636722›Full record

ArticleiLIVER2024

Risk factors for esophagogastric variceal-related poor outcomes in primary biliary cholangitis: A prospective cohort study.

Lin Han, Huan Xie, Xue-Mei Ma, Xiao-Long Lu, Jun Zhao, Qing-Sheng Liang, Zheng-Sheng Zou, Jing-Feng Bi, Bo Jin, Ying Sun

Abstract read
In one paragraph

Article in iLIVER, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lin HanSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Huan XieSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Xue-Mei MaSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Xiao-Long LuGraduate School, Medical School of Chinese PLA, Beijing 100039, China.
Jun ZhaoSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Qing-Sheng LiangSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Zheng-Sheng ZouSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Jing-Feng BiSenior Department of Infectious Diseases Medicine, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Bo JinSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.
Ying SunSenior Department of Hepatology, The Fifth Medical Center of PLA General Hospital, Beijing 100039, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Esophagogastric varices (EGV) are common complications of primary biliary cholangitis (PBC). We examined the risk factors for variceal bleeding-related liver transplantation (LT) or death. Methods: This prospective observational cohort study involved PBC in our hospital from 1 January 2005 to 1 January 2020. The clinical endpoints were variceal bleeding-related LT and death. Survival analysis was performed using the Kaplan-Meier estimate, cox regression analysis was performed to investigate risk factors. Results: PBC with EGV had significantly shorter survival than those without ( Conclusion: This study provides evidence that AST, INR and CHE are major risk factors for variceal bleeding-related poor outcomes in PBC. For PBC with EGV, a good biochemical response to UDCA and endoscopic prophylaxis may improve survival. These findings can aid for guiding initial PBC risk stratification and screening endoscopy in patients without EGV.

Indexed as

Endoscopic therapyEsophagogastric varicesLiver transplant-free survivalPrimary biliary cholangitisRisk factorsUrsodeoxycholic acid

Identifiers

PMID40636722
PMCPMC12212657

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.