Evidence map›Paper›PMID 40636609›Full record

ArticleCureus2025

Unexpected Digit: Isolated Acrometastasis to the Fifth Finger in Advanced Lung Cancer.

Zakaria Alameddine, Parima Saxena, Micha Gooden, Farish Mohamed, Elvira Neculiseanu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zakaria AlameddineOncology, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Parima SaxenaOncology, State University of New York Downstate Medical Center, Brooklyn, USA.
Micha GoodenOncology, State University of New York Downstate Medical Center, Brooklyn, USA.
Farish MohamedOncology, State University of New York Downstate Medical Center, Brooklyn, USA.
Elvira NeculiseanuOncology, State University of New York Downstate Medical Center, Brooklyn, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrometastasis is a rare manifestation of metastatic disease that affects the distal extremities and can occur as a complication of non-small-cell lung cancer. It is often associated with advanced disease and may coincide with other skeletal or systemic metastases. Management options typically include a combination of surgical intervention, radiation therapy, and systemic treatment. This report presents a case of an isolated acrometastatic lesion in the fifth digit of a patient with stage IV squamous cell carcinoma, without evidence of additional metastatic bone involvement. We explore diagnostic and therapeutic strategies for such presentations and emphasize the importance of a multidisciplinary approach in optimizing patient care. We also address the underlying pathophysiology and potential mechanisms contributing to acrometastatic spread.

Indexed as

acrometastasesamputationbone metastasesfifth digitlung squamous cell carcinoma

Identifiers

PMID40636609
PMCPMC12240538

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.